Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRPF1 | P55201 | 15/20 | 0.52 |
| ▸ | BRD1 | O95696 | 10/20 | 0.48 |
| ▸ | BRPF3 | Q9ULD4 | 7/20 | 0.48 |
| ▸ | BRD9 | Q9H8M2 | 4/20 | 0.48 |
| ▸ | BRD4 | O60885 | 4/20 | 0.48 |
| ▸ | BRD7 | Q9NPI1 | 2/20 | 0.48 |
| ▸ | PGR | P06401 | 1/20 | 0.45 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.45 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8029898 | 0.82 | BRPF1 (0.61) | BRPF1BRD1BRPF3BRD9BRD4 | |
| Hydrochloric Acid SCHEMBL8026367 | 0.81 | F2 (0.49) | BRPF1HDAC1HDAC8HDAC6 | |
| SCHEMBL8026334 | 0.76 | F2 (0.55) | BRPF1BRD1BRPF3BRD9BRD4 | |
| SCHEMBL8016775 | 0.74 | BRPF1 (0.41) | BRPF1BRD1BRPF3BRD9BRD4 | |
| SCHEMBL8030047 | 0.72 | KMT2A (0.46) | — | |
| SCHEMBL8032940 | 0.71 | KCNJ1 (0.48) | BRPF1RORC | |
| SCHEMBL8032933 | 0.71 | F2 (0.53) | BRD4 | |
| SCHEMBL8026422 | 0.69 | F2 (0.55) | BRPF1BRD1BRPF3BRD9BRD4 | |
| SCHEMBL8031758 | 0.68 | BRPF1 (0.40) | BRPF1BRD1RORC | |
| SCHEMBL8027395 | 0.68 | F2 (0.52) | BRPF1BRD1BRPF3BRD9BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1060166-A1 | FIVE-MEMBERED, BENZO-CONDENSED HETEROCYCLES USED AS ANTITHROMBOTIC AGENTS | Boehringer Ingelheim Pharma KG (DE) | 2000-12-20 | — | — | EP | disclosed |
| US-6114532-A | ANTICOAGULANT | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2000-09-05 | — | — | US | disclosed |
| WO-1999040072-A1 | FIVE-MEMBERED, BENZO-CONDENSED HETEROCYCLES USED AS ANTITHROMBOTIC AGENTS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 1999-08-12 | — | — | WO | disclosed |