Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.53 |
| ▸ | FAAH | O00519 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8029639 | 0.89 | SIGMAR1 (0.50) | SIGMAR1ALDH1A1KDM4ETDP1MEN1 | |
| SCHEMBL8029642 | 0.87 | SIGMAR1 (0.54) | SIGMAR1ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL8031421 | 0.82 | SIGMAR1 (0.48) | SIGMAR1ALDH1A1KDM4ETDP1L3MBTL1 | |
| SCHEMBL8020084 | 0.80 | FAAH (0.54) | SIGMAR1FAAHMAPTTSHRALDH1A1 | |
| SCHEMBL8035801 | 0.80 | NPC1 (0.46) | SIGMAR1ALDH1A1KDM4ETDP1GAA | |
| SCHEMBL8029877 | 0.80 | SIGMAR1 (0.50) | SIGMAR1FAAHTSHRALDH1A1KDM4E | |
| SCHEMBL8031455 | 0.79 | SIGMAR1 (0.53) | SIGMAR1ALDH1A1KDM4ETDP1HTT | |
| SCHEMBL8029891 | 0.78 | SIGMAR1 (0.50) | SIGMAR1FAAHTSHRALDH1A1KDM4E | |
| SCHEMBL8033363 | 0.77 | HRH3 (0.49) | SIGMAR1ALDH1A1KDM4EGAAMEN1 | |
| SCHEMBL8035814 | 0.77 | SIGMAR1 (0.49) | SIGMAR1ALDH1A1KDM4ETDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0702010-B1 | Benzopyranderivatives, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2000-03-15 | — | — | EP | disclosed |
| US-5668138-A | AFFINITY FOR SIGMA RECEPTORS, CENTRAL NERVOUS SYSTEM DISORDERS | ADIR ET COMPAGNIE (FR) | 1997-09-16 | — | — | US | disclosed |
| EP-0702010-A1 | Benzopyranderivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1996-03-20 | — | — | EP | disclosed |