Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2C | Q5R387 | 3/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | MMP14 | P50281 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 3/20 | 0.34 |
| ▸ | PPARA | Q07869 | 2/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15242342 | 0.92 | MMP9 (0.36) | PLA2G2CMMP9MMP8MMP14PPARG | |
| SCHEMBL8039425 | 0.81 | PLA2G2C (0.42) | PLA2G2CMMP9MMP8MMP14ATM | |
| SCHEMBL18391957 | 0.70 | HTT (0.45) | PPARAALDH1A1CYP3A4CYP2C19KDM4E | |
| Glutaconate SCHEMBL31023345 | 0.66 | HCAR2 (0.50) | EPHX2HCAR2ATMALDH1A1ALOX15 | |
| SCHEMBL5637940 | 0.65 | ALDH1A1 (0.60) | HCAR2ALDH1A1ALOX15CYP2D6CYP2C19 | |
| SCHEMBL2427567 | 0.65 | ALDH1A1 (0.60) | HCAR2ALDH1A1ALOX15CYP2D6CYP2C19 | |
| SCHEMBL10627343 | 0.65 | PLA2G2C (0.51) | PLA2G2CMMP9MMP8MMP14PPARG | |
| SCHEMBL21862469 | 0.65 | PLA2G2C (0.51) | PLA2G2CMMP9MMP8MMP14PPARG | |
| SCHEMBL15237379 | 0.65 | TSHR (0.36) | HCAR2ATMALDH1A1CYP3A4CYP2C19 | |
| SCHEMBL27291358 | 0.64 | CA2 (0.48) | ATMALDH1A1CYP3A4HSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009074605-A1 | AMINOTHIAZOLES AND THEIR USES | NOVARTIS AG (CH) | 2009-06-18 | — | — | WO | disclosed |