Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.83 |
| ▸ | LMNA | P02545 | 2/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.75 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.75 |
| ▸ | PKM | P14618 | 1/20 | 0.75 |
| ▸ | HPGD | P15428 | 1/20 | 0.71 |
| ▸ | HTT | P42858 | 1/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.70 |
| ▸ | CNR2 | P34972 | 2/20 | 0.69 |
| ▸ | ACHE | P22303 | 2/20 | 0.68 |
| ▸ | BCHE | P06276 | 1/20 | 0.68 |
| ▸ | MEN1 | O00255 | 2/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.68 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.68 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.68 |
| ▸ | TYR | P14679 | 1/20 | 0.67 |
| ▸ | MAOA | P21397 | 1/20 | 0.64 |
| ▸ | MAOB | P27338 | 1/20 | 0.64 |
| ▸ | MMP1 | P03956 | 1/20 | 0.62 |
| ▸ | MMP2 | P08253 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28994634 | 0.93 | CNR2 (0.79) | MAPTLMNAALDH1A1KDM4EPKM | |
| SCHEMBL17956818 | 0.93 | CNR2 (0.79) | MAPTLMNAALDH1A1KDM4EPKM | |
| SCHEMBL17956817 | 0.93 | CNR2 (0.79) | MAPTLMNAALDH1A1KDM4EPKM | |
| SCHEMBL30354371 | 0.93 | CNR2 (0.79) | MAPTLMNAALDH1A1KDM4EPKM | |
| SCHEMBL802998 | 0.92 | ACHE (0.79) | MAPTLMNAALDH1A1KDM4EPKM | |
| SCHEMBL1917252 | 0.91 | MAPT (0.84) | MAPTLMNAALDH1A1KDM4EPKM | |
| SCHEMBL31286546 | 0.91 | MAPT (0.84) | MAPTLMNAALDH1A1KDM4EPKM | |
| SCHEMBL1917292 | 0.91 | MAPT (0.84) | MAPTLMNAALDH1A1KDM4EPKM | |
| SCHEMBL32679235 | 0.91 | MAPT (0.84) | MAPTLMNAALDH1A1KDM4EPKM | |
| SCHEMBL4812487 | 0.91 | MAPT (0.84) | MAPTLMNAALDH1A1KDM4EPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9295624-B2 | Amide derivative and whitening agent | AJINOMOTO CO., INC. (JP) | 2016-03-29 | — | — | US | disclosed |
| EP-2412701-B1 | NOVEL AMIDE DERIVATIVE AND SKIN WHITENING AGENT | AJINOMOTO KK (JP) | 2015-08-12 | — | — | EP | disclosed |
| US-20140255327-A1 | NOVEL AMIDE DERIVATIVE AND WHITENING AGENT | AJINOMOTO CO. INC. (JP) | 2014-09-11 | — | — | US | disclosed |
| US-20120070395-A1 | NOVEL AMIDE DERIVATIVE AND WHITENING AGENT | AJINOMOTO CO. INC (JP) | 2012-03-22 | — | — | US | disclosed |
| EP-2412701-A1 | NOVEL AMIDE DERIVATIVE AND SKIN WHITENING AGENT | Ajinomoto Co., Inc. (JP) | 2012-02-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140255327-A1 | NOVEL AMIDE DERIVATIVE AND WHITENING AGENT | CUTA, NAT1, TYR | MAPT 1419/4885LMNA 2148/4885ALDH1A1 163/4885 |
| US-20120070395-A1 | NOVEL AMIDE DERIVATIVE AND WHITENING AGENT | CUTA, NAT1, TYR | MAPT 1419/4885LMNA 2148/4885ALDH1A1 163/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.