Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC5A2 | P31639 | 1/20 | 0.44 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GALR3 | O60755 | 1/20 | 0.40 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7410652 | 0.82 | MAPT (0.42) | CXCR3POLBGALR3NR2F2 | |
| SCHEMBL7415589 | 0.81 | TP53 (0.44) | CXCR3KMT2APOLBGALR3NR2F2 | |
| SCHEMBL8030047 | 0.80 | KMT2A (0.46) | SLC5A2KMT2A | |
| SCHEMBL8801466 | 0.80 | SLC5A2 (0.45) | SLC5A2POLB | |
| SCHEMBL7410648 | 0.80 | RORC (0.42) | CXCR3KMT2APOLBGALR3NR2F2 | |
| SCHEMBL7412913 | 0.80 | THRB (0.47) | CXCR3POLBGALR3NR2F2 | |
| SCHEMBL8801731 | 0.79 | TSHR (0.40) | CXCR3POLBGALR3NR2F2 | |
| SCHEMBL8801906 | 0.79 | CNR2 (0.46) | POLB | |
| SCHEMBL8803243 | 0.78 | CNR2 (0.46) | POLB | |
| SCHEMBL7409597 | 0.78 | CNR2 (0.46) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640080-B1 | SUBSTITUTED INDOLES AS ANGIOTENSIN II ANTAGONISTS | SYNTEX INC (US) | 1997-10-22 | — | — | EP | disclosed |
| EP-0640080-A1 | SUBSTITUTED INDOLES AND AZAINDOLES AS ANGIOTENSIN II ANTAGONISTS. | SYNTEX INC (US) | 1995-03-01 | — | — | EP | disclosed |
| US-5380739-A | Angiotensin II antagonists | SYNTEX (U.S.A.) INC. (US) | 1995-01-10 | — | — | US | disclosed |
| WO-1993023391-A1 | SUBSTITUTED INDOLES AND AZAINDOLES AS ANGIOTENSIN II ANTAGONISTS | SYNTEX (U.S.A.) INC. (US) | 1993-11-25 | — | — | WO | disclosed |