Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 2/20 | 0.37 |
| ▸ | MYC | P01106 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8037033 | 1.00 | BACE1 (0.43) | BACE1MMP9MYCALDH1A1MAPT | |
| SCHEMBL8021153 | 0.84 | MMP9 (0.44) | MMP9ALDH1A1MAPTSMN1; SMN2CES2 | |
| SCHEMBL8021154 | 0.84 | MMP9 (0.44) | MMP9ALDH1A1MAPTSMN1; SMN2CES2 | |
| SCHEMBL8030538 | 0.83 | NPC1 (0.37) | BACE1MMP9ALDH1A1MAPTITGA4 | |
| SCHEMBL8030536 | 0.83 | NPC1 (0.37) | BACE1MMP9ALDH1A1MAPTITGA4 | |
| SCHEMBL6428933 | 0.80 | ALDH1A1 (0.40) | MMP9ALDH1A1MAPTITGA4TRPM8 | |
| SCHEMBL6428936 | 0.80 | ALDH1A1 (0.40) | MMP9ALDH1A1MAPTITGA4TRPM8 | |
| SCHEMBL19365539 | 0.80 | ALDH1A1 (0.40) | MMP9ALDH1A1MAPTITGA4TRPM8 | |
| SCHEMBL8034368 | 0.79 | TSHR (0.40) | — | |
| SCHEMBL7227003 | 0.78 | USP1 (0.42) | MMP9ALDH1A1MAPTITGA4SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6127546-A | Process for the preparation of oxazoline compound | DONG KOOK PHARMACEUTICAL CO., LTD. (KR) | 2000-10-03 | — | — | US | disclosed |