Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.44 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.44 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 3/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6730883 | 0.79 | LMNA (0.50) | ALDH1A1KMT2AMEN1 | |
| SCHEMBL11647775 | 0.70 | DDB1 (0.56) | DDB1CRBNHTR2CALDH1A1MAPT | |
| SCHEMBL24877574 | 0.69 | DRD2 (0.62) | DRD2HTR2CKDM1ARCOR1HTR2A | |
| SCHEMBL5339211 | 0.68 | ALDH1A1 (0.62) | ALDH1A1KMT2AMEN1 | |
| SCHEMBL11083722 | 0.67 | DRD2 (0.59) | DRD2DDB1CRBNHTR2CCHRNA7 | |
| SCHEMBL6385829 | 0.66 | DDB1 (0.55) | DDB1CRBNHTR2CKDM1ARCOR1 | |
| SCHEMBL1268402 | 0.66 | PDE4A (0.62) | DDB1CRBNHTR2CKDM4EALDH1A1 | |
| SCHEMBL10508333 | 0.66 | HTR2C (0.51) | DDB1CRBNHTR2CKDM1ARCOR1 | |
| SCHEMBL8350724 | 0.66 | DRD2 (0.79) | DRD2HTR2C | |
| SCHEMBL8041637 | 0.66 | PDE4A (0.62) | DDB1CRBNHTR2CKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0981320-A1 | COMPOSITION FOR DYEING KERATIN FIBRES COMPRISING A PYRAZOLIN-4,5-DIONE AND AN AROMATIC PRIMARY AMINE | L'OREAL (FR) | 2000-03-01 | — | — | EP | disclosed |
| WO-1998051268-A1 | COMPOSITION FOR DYEING KERATIN FIBRES COMPRISING A PYRAZOLIN-4,5-DIONE AND AN AROMATIC PRIMARY AMINE | L'OREAL (FR) | 1998-11-19 | — | — | WO | disclosed |