Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 1/20 | 0.54 |
| ▸ | CYP2A6 | P11509 | 8/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | SNCA | P37840 | 1/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | AXL | P30530 | 1/20 | 0.46 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.46 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.46 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | CYP2E1 | P05181 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12279413 | 0.81 | HPGDS (0.71) | HPGDSCYP2A6CYP3A4ALDH1A1KDM4E | |
| SCHEMBL928439 | 0.80 | SNCA (0.55) | HPGDSALDH1A1KDM4ESMN1; SMN2CYP1A2 | |
| SCHEMBL2498473 | 0.79 | SNCA (0.53) | CYP3A4ALDH1A1KDM4ESMN1; SMN2CYP1A2 | |
| SCHEMBL16601901 | 0.78 | KDM4E (0.59) | HPGDSCYP2A6CYP3A4ALDH1A1KDM4E | |
| SCHEMBL2820252 | 0.78 | HPGDS (0.54) | HPGDSCYP2A6CYP3A4ALDH1A1KDM4E | |
| SCHEMBL15090524 | 0.77 | SNCA (0.56) | HPGDSALDH1A1KDM4ESMN1; SMN2CYP1A2 | |
| Hydrochloric Acid SCHEMBL17101469 | 0.76 | KDM4E (0.57) | HPGDSCYP2A6CYP3A4ALDH1A1KDM4E | |
| SCHEMBL7862948 | 0.76 | SNCA (0.50) | HPGDSCYP2A6SNCA | |
| SCHEMBL255577 | 0.76 | KDM4E (0.66) | CYP2A6CYP3A4ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL30803985 | 0.76 | KDM4E (0.66) | CYP2A6CYP3A4ALDH1A1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117561252-A | 2- [3- [1[ (quinazolin-4-yl) amino ] ethyl ] pyrazin-2-yl ] thiazole-5-carbonitrile derivatives and similar compounds as pesticides | 先正达农作物保护股份公司 | 2024-02-13 | — | — | CN | disclosed |
| US-20150166528-A1 | Pesticidal methods using substituted 3-pyridyl thiazole compounds and derivatives for combating animal pests | BASF SE (DE) | 2015-06-18 | — | — | US | disclosed |
| US-20150166528-A1 | Pesticidal methods using substituted 3-pyridyl thiazole compounds and derivatives for combating animal pests | BASF SE (DE) | 2015-06-18 | — | — | US | disclosed |
| CN-1343215-A | 6-O-substituted macrolides with antibacterial activity | ABBOTT LAB (US) | 2002-04-03 | — | — | CN | disclosed |
| US-6054435-A | 6-O-substituted macrolides having antibacterial activity | ABBOTT LABORATORIES (US) | 2000-04-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150166528-A1 | Pesticidal methods using substituted 3-pyridyl thiazole compounds and derivatives for combating animal pests | PTMS, PDXK, TH | HPGDS 2618/4885CYP2A6 1875/4885CYP3A4 933/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.