Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | FAAH | O00519 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8029589 | 0.89 | TSHR (0.61) | MEN1KMT2AALDH1A1SMN1; SMN2TSHR | |
| Hydrochloric Acid SCHEMBL8887455 | 0.88 | TSHR (0.60) | MEN1KMT2AALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL8035824 | 0.86 | SMN1; SMN2 (0.52) | MEN1KMT2AALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL8033227 | 0.83 | ALDH1A1 (0.59) | KMT2AALDH1A1SMN1; SMN2TSHRHSD17B10 | |
| SCHEMBL8033255 | 0.82 | SMN1; SMN2 (0.56) | MEN1KMT2AALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL8035741 | 0.81 | ALDH1A1 (0.54) | MEN1KMT2AALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL8020104 | 0.81 | LMNA (0.59) | MEN1KMT2AALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL8910223 | 0.81 | KMT2A (0.61) | MEN1KMT2AALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL8035814 | 0.80 | SIGMAR1 (0.49) | MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL5064012 | 0.80 | ALDH1A1 (0.56) | MEN1KMT2AALDH1A1SMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0702010-B1 | Benzopyranderivatives, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2000-03-15 | — | — | EP | disclosed |
| US-5668138-A | AFFINITY FOR SIGMA RECEPTORS, CENTRAL NERVOUS SYSTEM DISORDERS | ADIR ET COMPAGNIE (FR) | 1997-09-16 | — | — | US | disclosed |
| EP-0702010-A1 | Benzopyranderivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1996-03-20 | — | — | EP | disclosed |