Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.61 |
| ▸ | MEN1 | O00255 | 4/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | FAAH | O00519 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8029589 | 0.91 | TSHR (0.61) | KMT2AMEN1ALDH1A1SMN1; SMN2FAAH | |
| Hydrochloric Acid SCHEMBL8887455 | 0.90 | TSHR (0.60) | KMT2AMEN1ALDH1A1SMN1; SMN2FAAH | |
| SCHEMBL8033255 | 0.89 | SMN1; SMN2 (0.56) | KMT2AMEN1ALDH1A1SMN1; SMN2FAAH | |
| SCHEMBL8020104 | 0.88 | LMNA (0.59) | KMT2AMEN1ALDH1A1SMN1; SMN2FAAH | |
| SCHEMBL8035741 | 0.88 | ALDH1A1 (0.54) | KMT2AMEN1ALDH1A1SMN1; SMN2FAAH | |
| SCHEMBL8033227 | 0.83 | ALDH1A1 (0.59) | KMT2AALDH1A1SMN1; SMN2FAAHTSHR | |
| SCHEMBL8033220 | 0.81 | ALDH1A1 (0.58) | KMT2AMEN1ALDH1A1SMN1; SMN2FAAH | |
| SCHEMBL8035824 | 0.81 | SMN1; SMN2 (0.52) | KMT2AMEN1ALDH1A1SMN1; SMN2FAAH | |
| SCHEMBL8031495 | 0.81 | MEN1 (0.56) | KMT2AMEN1ALDH1A1SMN1; SMN2FAAH | |
| SCHEMBL8020002 | 0.80 | SMN1; SMN2 (0.53) | KMT2AMEN1ALDH1A1SMN1; SMN2FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5668138-A | AFFINITY FOR SIGMA RECEPTORS, CENTRAL NERVOUS SYSTEM DISORDERS | ADIR ET COMPAGNIE (FR) | 1997-09-16 | — | — | US | disclosed |