Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Biphenyl. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.50 |
| ▸ | MMP3 | P08254 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | BACE1 | P56817 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.46 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.46 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.44 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.44 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Biphenyl SCHEMBL8855942 | 1.00 | ALDH1A1 (0.60) | ALDH1A1SMN1; SMN2MAPTL3MBTL1BCL2L1 | |
| Biphenyl SCHEMBL28026828 | 0.97 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2MAPTL3MBTL1BCL2L1 | |
| Biphenyl SCHEMBL7872913 | 0.91 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2MAPTL3MBTL1BCL2L1 | |
| Biphenyl SCHEMBL20583591 | 0.88 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2MAPTL3MBTL1BCL2L1 | |
| Biphenyl SCHEMBL1815228 | 0.87 | WDR5 (0.54) | ALDH1A1SMN1; SMN2MAPTL3MBTL1BCL2L1 | |
| Biphenyl SCHEMBL10601883 | 0.87 | ALDH1A1 (0.45) | ALDH1A1SMN1; SMN2MAPTL3MBTL1BCL2L1 | |
| Biphenyl SCHEMBL7178645 | 0.87 | SMN1; SMN2 (0.59) | ALDH1A1SMN1; SMN2MAPTL3MBTL1HPGD | |
| Biphenyl SCHEMBL23270852 | 0.86 | ALDH1A1 (0.69) | ALDH1A1SMN1; SMN2MAPTL3MBTL1BCL2L1 | |
| Biphenyl SCHEMBL323849 | 0.86 | ALDH1A1 (0.69) | ALDH1A1SMN1; SMN2MAPTL3MBTL1BCL2L1 | |
| Biphenyl SCHEMBL7871199 | 0.84 | CYP3A4 (0.57) | ALDH1A1SMN1; SMN2MAPTL3MBTL1BCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 743 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119345485-A | Preparation method of degradable antibacterial function silk fibroin medical melarsoid | 苏州大学 | 2025-01-24 | — | — | CN | claimed |
| CN-109244104-B | Optical filter of organic light emitting device and organic light emitting device including the same | 东进世美肯株式会社 | 2024-09-17 | — | — | CN | claimed |
| CN-220918174-U | Biphenyl alcohol chlorination rectifying vacuum device | 上海慕洋生物科技有限公司 | 2024-05-10 | — | — | CN | claimed |
| CN-220834165-U | Distillation still for producing diphenyl alcohol | 上海慕洋生物科技有限公司 | 2024-04-26 | — | — | CN | claimed |
| CN-220758904-U | Stirring kettle for producing diphenyl alcohol | 上海慕洋生物科技有限公司 | 2024-04-12 | — | — | CN | claimed |
| CN-117756630-A | Method for synthesizing bifenthrin by using ebullated bed | 江苏优嘉植物保护有限公司 | 2024-03-26 | — | — | CN | claimed |
| CN-115433056-B | Preparation method of biphenyl alcohol intermediate | 上海炎宁生物科技有限公司 | 2024-03-15 | — | — | CN | claimed |
| CN-113788754-B | Preparation method of bifenthrin | 北京怡力生物科技有限公司 | 2023-10-24 | — | — | CN | claimed |
| CN-116764459-A | Preparation method of COFs/PAN oil-water separation microporous membrane with submerged super-amphiphobicity | 山东中康国创先进印染技术研究院有限公司 | 2023-09-19 | — | — | CN | claimed |
| CN-111087307-B | O-phenyl phenoxyalkyl acrylate and preparation method thereof | 台湾中国石油化学工业开发股份有限公司 | 2023-08-01 | — | — | CN | claimed |
| CN-103539667-A | Preparation method of low chroma o-phenyl phenoxyethyl acrylic ester | SHANGHAI WEIKAI CHEMICALS CO | 2014-01-29 | — | — | CN | claimed |
| CN-102432475-A | Acid-alkali two-component gelator based on 2-amino-1,2-diphenylethanol | UNIV HUAZHONG SCIENCE TECH | 2012-05-02 | — | — | CN | claimed |
| CN-101195602-B | 1-deoxidization nojiri toxin derivant, production method and uses thereof | UNIV ZHENGZHOU | 2011-03-23 | — | — | CN | claimed |
| CN-101959980-A | Antireflective coating composition | AZ ELECTRONIC MATERIALS USA | 2011-01-26 | — | — | CN | claimed |
| CN-101195602-A | 1-deoxidization nojiri toxin derivant, production method and uses thereof | UNIV ZHENGZHOU (CN) | 2008-06-11 | — | — | CN | claimed |
| CN-1235851-C | Method for producing alkenyl ethers | BASF AG (DE) | 2006-01-11 | — | — | CN | claimed |
| CN-1319595-A | Method for producing optically active 3-hydroxy-gamna-butyrolactone | KURARAY CO (JP) | 2001-10-31 | — | — | CN | claimed |
| CN-1070469-C | Optical resolution method of (+/-) -3, 4-dihydroxybutyric acid | KURARAY CO (JP) | 2001-09-05 | — | — | CN | claimed |
| US-5853728-A | Polyphenolic cosmetic composition | THE NIKKA WHISKY DISTILLING CO., LTD. (JP) | 1998-12-29 | — | — | US | claimed |
| CN-1184806-A | Optical resolution method of (+/-) -3, 4-dihydroxybutyric acid | KURARAY CO (JP) | 1998-06-17 | — | — | CN | claimed |