Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.52 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.52 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.47 |
| ▸ | CSF1R | P07333 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.45 |
| ▸ | ALPL | P05186 | 1/20 | 0.44 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.43 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PTGES | O14684 | 1/20 | 0.43 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.42 |
| ▸ | TNKS | O95271 | 1/20 | 0.42 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8036853 | 0.91 | SIRT2 (0.54) | SIRT2SIRT1SIRT3TP53MDM2 | |
| SCHEMBL8026733 | 0.85 | SIRT2 (0.56) | SIRT2SIRT1SIRT3TP53MDM2 | |
| SCHEMBL4010739 | 0.82 | SIRT2 (0.45) | SIRT2SIRT1SIRT3ALOX5ALPL | |
| SCHEMBL8022429 | 0.81 | SIRT2 (0.52) | SIRT2SIRT1SIRT3TP53MDM2 | |
| SCHEMBL8042850 | 0.81 | ALDH1A1 (0.47) | SIRT2SIRT1SIRT3TARBP2MAPT | |
| SCHEMBL8038397 | 0.80 | TARBP2 (0.49) | SIRT2SIRT1SIRT3TP53MDM2 | |
| Oxalic Acid SCHEMBL31679107 | 0.75 | SIRT2 (0.44) | SIRT2SIRT1SIRT3TNKSTNKS2 | |
| SCHEMBL8762855 | 0.74 | HSD17B10 (0.52) | TP53CSF1RLMNAMAPTALDH1A1 | |
| SCHEMBL8043111 | 0.74 | SMN1; SMN2 (0.46) | SIRT2SIRT1SIRT3MAPTTNKS | |
| SCHEMBL23736192 | 0.74 | HEXA (0.47) | SIRT2SIRT1SIRT3ALDH1A1TNKS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009080248-A1 | SUBSTITUTED 2-PHENYLPYRIMIDINE-5-CARBOXYLIC ACIDS AND THE USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-07-02 | — | — | WO | disclosed |