Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TARBP2 | Q15633 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.48 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.47 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.47 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.47 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.46 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.46 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALPL | P05186 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8032185 | 0.88 | LMNA (0.45) | TARBP2MAPTPRKCZTRPM8RAB9A | |
| SCHEMBL8037054 | 0.86 | KDM4E (0.50) | TARBP2MAPTPRKCZTRPM8RAB9A | |
| SCHEMBL8036404 | 0.85 | CYP1A2 (0.43) | TARBP2MAPTPRKCZTRPM8RAB9A | |
| SCHEMBL8034697 | 0.84 | MAPT (0.40) | TARBP2MAPTPRKCZTRPM8RAB9A | |
| SCHEMBL8034254 | 0.83 | LMNA (0.42) | TARBP2MAPTPRKCZTRPM8RAB9A | |
| SCHEMBL8040307 | 0.83 | GABRA2 (0.49) | TARBP2MAPTPRKCZTRPM8RAB9A | |
| SCHEMBL8032162 | 0.80 | SIRT2 (0.52) | TARBP2MAPTPRKCZTRPM8TP53 | |
| SCHEMBL4007701 | 0.80 | CTRC (0.41) | MAPTRAB9ATP53KDM4EMEN1 | |
| SCHEMBL8036018 | 0.80 | KDM4E (0.56) | TARBP2MAPTPRKCZTRPM8RAB9A | |
| SCHEMBL11494053 | 0.78 | KDM4E (0.73) | MAPTRAB9ATP53KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009080248-A1 | SUBSTITUTED 2-PHENYLPYRIMIDINE-5-CARBOXYLIC ACIDS AND THE USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-07-02 | — | — | WO | disclosed |