Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 1/20 | 0.53 |
| ▸ | PPARG | P37231 | 10/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.44 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.43 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8034344 | 0.86 | PPARG (0.54) | SLC6A9PPARGMEN1KMT2AMAPT | |
| SCHEMBL8034144 | 0.83 | MAPT (0.66) | SLC6A9PPARGMEN1KMT2AMAPT | |
| SCHEMBL8024501 | 0.82 | POLB (0.46) | SLC6A9PPARGMEN1KMT2AKCNA5 | |
| SCHEMBL4537762 | 0.78 | PPARG (0.48) | PPARGMAPTKCNA5HDAC8HDAC1 | |
| SCHEMBL8036185 | 0.78 | PPARG (0.54) | PPARGSSTR3HDAC8HDAC1HDAC6 | |
| SCHEMBL4540765 | 0.77 | MEN1 (0.52) | SLC6A9PPARGMEN1KMT2AMAPT | |
| SCHEMBL4537211 | 0.75 | KCNK3 (0.50) | PPARGMAPTHDAC8HDAC1HDAC6 | |
| SCHEMBL4540776 | 0.75 | MAPT (0.63) | MEN1KMT2AMAPTRXFP1 | |
| SCHEMBL8040416 | 0.74 | PPARG (0.58) | PPARGMEN1KMT2AKCNA5 | |
| SCHEMBL8032490 | 0.74 | PPARG (0.55) | PPARGHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009083526-A1 | NOVEL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-07-09 | — | — | WO | disclosed |