Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 6/20 | 0.43 |
| ▸ | TACR3 | P29371 | 2/20 | 0.41 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.40 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8034302 | 0.86 | POLB (0.45) | POLBPPARGKCNA5HPGDKDM4E | |
| SCHEMBL8028605 | 0.86 | POLB (0.45) | POLBPPARGKCNA5HPGDKDM4E | |
| SCHEMBL8036319 | 0.83 | MAPT (0.49) | MEN1KMT2AHPGDPKM | |
| SCHEMBL8032170 | 0.82 | SLC6A9 (0.53) | PPARGKCNA5MEN1KMT2ASLC6A9 | |
| SCHEMBL4537762 | 0.71 | PPARG (0.48) | PPARGKCNA5HPGDKDM4EALDH1A1 | |
| SCHEMBL8022765 | 0.70 | KCNK3 (0.50) | PPARGKCNK3 | |
| SCHEMBL8036185 | 0.70 | PPARG (0.54) | PPARGTAS1R3TAS1R1 | |
| SCHEMBL8032490 | 0.69 | PPARG (0.55) | PPARG | |
| SCHEMBL8038260 | 0.69 | PPARG (0.71) | PPARG | |
| SCHEMBL4660820 | 0.68 | KDM4E (0.67) | PPARGTACR3KCNA5MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009083526-A1 | NOVEL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-07-09 | — | — | WO | disclosed |