SCHEMBL8032436

SCHEMBL8032436

COCC(=O)Nc1ccc2c(Cl)c(O)ccc2c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4C Q9H3R0 2/20 0.58
▸ HPGD P15428 5/20 0.56
▸ KMT2A Q03164 1/20 0.53
▸ ALDH1A1 P00352 3/20 0.49
▸ SMN1; SMN2 Q16637 2/20 0.49
▸ KDM4E B2RXH2 1/20 0.47
▸ L3MBTL1 Q9Y468 1/20 0.47
▸ KDM5A P29375 1/20 0.46
▸ KDM4D Q6B0I6 1/20 0.46
▸ KDM5B Q9UGL1 1/20 0.46
▸ KDM2A Q9Y2K7 1/20 0.46
▸ KDM3A Q9Y4C1 1/20 0.46
▸ MAPT P10636 2/20 0.46
▸ CYP2C19 P33261 1/20 0.46
▸ ALOX12 P18054 1/20 0.46
▸ MAPK1 P28482 1/20 0.46
▸ HTT P42858 1/20 0.46
▸ ITK Q08881 1/20 0.44
▸ RAB9A P51151 1/20 0.43
▸ LMNA P02545 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8032034 0.80 HSD17B1 (0.49) KMT2AALDH1A1SMN1; SMN2KDM4EMAPT
SCHEMBL7751121 0.80 HPGD (0.73) KDM4CHPGDKMT2AALDH1A1SMN1; SMN2
SCHEMBL14962804 0.73 HPGD (0.81) KDM4CHPGDKMT2AALDH1A1SMN1; SMN2
SCHEMBL2091479 0.72 HPGD (0.70) HPGDKMT2AALDH1A1SMN1; SMN2L3MBTL1
SCHEMBL15627957 0.72 ALDH1A1 (0.73) KDM4CHPGDKMT2AALDH1A1SMN1; SMN2
SCHEMBL14426553 0.72 HPGD (0.78) KDM4CHPGDKMT2AALDH1A1SMN1; SMN2
SCHEMBL9298899 0.71 HPGD (0.67) KDM4CHPGDALDH1A1SMN1; SMN2KDM4E
SCHEMBL19860094 0.70 NOTUM (0.68) —
SCHEMBL1976948 0.70 HPGD (0.71) KDM4CHPGDKMT2AALDH1A1SMN1; SMN2
SCHEMBL9495103 0.70 SMN1; SMN2 (0.71) KDM4CHPGDKMT2AALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0603954-B1 Immunoassay using a 4-hydroxy or 4-alkoxyarylacetamide as stabilizer JOHNSON & JOHNSON CLIN DIAG (US) 2000-03-08 — — EP disclosed
EP-0603953-B1 Use of 4' of 5'-hydroxy and 4'- or 5'-alkoxy-substituted electron transfer agents in compositions, elements, test kits and analytical methods JOHNSON & JOHNSON CLIN DIAG (US) 1999-02-17 — — EP disclosed
US-5736335-A Dry elements, test devices, test kits and methods for chemiluminescent detection of analytes using peroxidase-labeled reagents EASTMAN KODAK COMPANY (US) 1998-04-07 — — US disclosed
US-5641635-A Dry elements, test devices, test kits and methods for chemiluminescent detection of analytes using peroxidase-labeled reagents EASTMAN KODAK COMPANY (US) 1997-06-24 — — US disclosed
US-5372931-A Use of 4'-hydroxy- and 4'-alkoxy-substituted electron transfer agents in compositions, elements, test kits and analytical methods EASTMAN KODAK COMPANY (US) 1994-12-13 — — US disclosed
US-5372932-A Peroxidase-labeled immunoreactant; stabiliztion with a 4-hydroxy or 4-alkoxyarylacetamide EASTMAN KODAK COMPANY (US) 1994-12-13 — — US disclosed
EP-0603953-A1 Use of 4' of 5'-hydroxy and 4'- or 5'-alkoxy-substituted electron transfer agents in compositions, elements, test kits and analytical methods Johnson & Johnson Clinical Diagnostics, Inc. (US) 1994-06-29 — — EP disclosed
EP-0603954-A2 Analytical element and immunoassay using a 4-hydroxy or 4-alkoxyarylacetamide as stabilizer Johnson & Johnson Clinical Diagnostics, Inc. (US) 1994-06-29 — — EP disclosed
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