⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2009378 | 0.97 | TSHR (0.52) | — | |
| SCHEMBL4756766 | 0.97 | TSHR (0.52) | — | |
| SCHEMBL1585548 | 0.97 | TSHR (0.52) | — | |
| SCHEMBL4754038 | 0.97 | TSHR (0.52) | — | |
| SCHEMBL4755755 | 0.97 | TSHR (0.52) | — | |
| SCHEMBL1948712 | 0.97 | TSHR (0.52) | — | |
| SCHEMBL2153463 | 0.97 | TSHR (0.52) | — | |
| SCHEMBL4757186 | 0.97 | TSHR (0.52) | — | |
| SCHEMBL4755731 | 0.97 | TSHR (0.52) | — | |
| SCHEMBL4755758 | 0.97 | TSHR (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 3931 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240182955-A1 | DNA FRAGMENT JOINING DETECTING METHOD AND KIT THEREOF | Act Genomics (ip) Limited (HK) | 2024-06-06 | — | — | US | claimed |
| US-20240167040-A1 | ANTISENSE OLIGONUCLEOTIDE | HOFFMANN LA ROCHE (US) | 2024-05-23 | — | — | US | claimed |
| CN-118006613-A | Aptamer-siRNA fusions | 艾普特纳有限公司 | 2024-05-10 | — | — | CN | claimed |
| US-20240150431-A1 | MHC Multimers, Methods for Their Generation, Labeling and Use | DAKO DENMARK APS (DK) | 2024-05-09 | — | — | US | claimed |
| EP-4361271-A2 | APTAMER-SIRNA FUSIONS | Apterna Limited (GB) | 2024-05-01 | — | — | EP | claimed |
| CN-117412752-A | Application of 4-arylaminoquinazoline hydroxamic acid compound in preparation of pain medicines | 广东众生药业股份有限公司 | 2024-01-16 | — | — | CN | claimed |
| EP-4294945-A1 | DNA FRAGMENT JOINING DETECTING METHOD AND KIT THEREOF | Act Genomics (IP) Limited (CN) | 2023-12-27 | — | — | EP | claimed |
| CN-117222750-A | DNA fragment junction detection method and kit | 行动基因(智财)有限公司 | 2023-12-12 | — | — | CN | claimed |
| CN-117126180-A | Biphenyl compound as immunomodulator as well as preparation method and application thereof | 深圳微芯生物科技股份有限公司 | 2023-11-28 | — | — | CN | claimed |
| WO-2023167923-A1 | SURFACE MODIFICATION OF NALNF4 NANOPARTICLES WITH BISPHOSPHONATE DERIVATIVES FOR MASS CYTOMETRY APPLICATIONS | STANDARD BIOTOOLS CANADA INC. (CA) | 2023-09-07 | — | — | WO | claimed |
| EP-0144957-A2 | Process for purifying factor VIII:C | Armour Pharmaceutical Company (US) | 1985-06-19 | — | — | EP | claimed |
| US-4508709-A | ADSORPTION, ELUTION FORM AMINOHEXYL AGAROSE | ARMOUR PHARMACEUTICAL COMPANY (US) | 1985-04-02 | — | — | US | claimed |
| EP-0125056-A2 | Condensed, seven-membered ring compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1984-11-14 | — | — | EP | claimed |
| EP-0083483-A1 | Ultrapurificated factor VIII : C preparation | SCRIPPS CLINIC AND RESEARCH FOUNDATION (US) | 1983-07-13 | — | — | EP | claimed |
| WO-1983002114-A1 | ULTRAPURIFICATION OF FACTOR VIII | SCRIPPS CLINIC RES (US) | 1983-06-23 | — | — | WO | claimed |
| US-4361509-A | Ultrapurification of factor VIII using monoclonal antibodies | SCRIPPS CLINIC AND RESEARCH FOUNDATION (US) | 1982-11-30 | — | — | US | claimed |
| US-4336188-A | Method for the preparation of macromolecularized adenine derivatives | SNAMPROGETTI, S.P.A. (IT) | 1982-06-22 | — | — | US | claimed |
| US-4205130-A | AFFINITY VHROMATORGAPHY, ISOELECTRIC FOCUSING | VIHKO PIRKKO | 1980-05-27 | — | — | US | claimed |
| US-3983117-A | OPTICAL BRIGHTENERS | BASF AKTIENGESELLSCHAFT (DT) | 1976-09-28 | — | — | US | claimed |
| US-3953596-A | 8-Oxa-3-azabicyclo(3.2.1)octane analgesic compositions and method of alleviating pain in animals | ICI UNITED STATES INC. (US) | 1976-04-27 | — | — | US | claimed |