Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 10/20 | 0.87 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.76 |
| ▸ | MAPK11 | Q15759 | 14/20 | 0.66 |
| ▸ | MAPK14 | Q16539 | 14/20 | 0.66 |
| ▸ | MAPK13 | O15264 | 13/20 | 0.66 |
| ▸ | GCGR | P47871 | 13/20 | 0.66 |
| ▸ | MAPK12 | P53778 | 13/20 | 0.66 |
| ▸ | CSNK1A1 | P48729 | 5/20 | 0.66 |
| ▸ | CSNK1D | P48730 | 5/20 | 0.66 |
| ▸ | PRKD3 | O94806 | 4/20 | 0.66 |
| ▸ | MAP4K4 | O95819 | 4/20 | 0.66 |
| ▸ | FRK | P42685 | 4/20 | 0.66 |
| ▸ | MAPK9 | P45984 | 4/20 | 0.66 |
| ▸ | GSK3B | P49841 | 4/20 | 0.66 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.66 |
| ▸ | PTK6 | Q13882 | 3/20 | 0.66 |
| ▸ | PRKD2 | Q9BZL6 | 3/20 | 0.66 |
| ▸ | TCF4 | P15884 | 1/20 | 0.59 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.59 |
| ▸ | PRKACA | P17612 | 3/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4551864 | 0.93 | ALOX5 (1.00) | ALOX5NOX1MAPK11MAPK14MAPK13 | |
| SCHEMBL1071183 | 0.86 | NOX1 (1.00) | ALOX5NOX1MAPK11MAPK14MAPK13 | |
| SCHEMBL8032578 | 0.85 | NOX1 (0.76) | ALOX5NOX1MAPK11MAPK14MAPK13 | |
| SCHEMBL6468252 | 0.85 | NOX1 (0.76) | ALOX5NOX1MAPK11MAPK14MAPK13 | |
| SCHEMBL9436010 | 0.84 | ALOX5 (0.64) | ALOX5NOX1MAPK11MAPK14MAPK13 | |
| SCHEMBL6467424 | 0.82 | NOX1 (0.72) | ALOX5NOX1MAPK11MAPK14MAPK13 | |
| SCHEMBL3371979 | 0.82 | MAPK14 (0.74) | ALOX5MAPK11MAPK14MAPK13GCGR | |
| SCHEMBL1629037 | 0.81 | MAPK13 (0.85) | ALOX5NOX1MAPK11MAPK14MAPK13 | |
| SCHEMBL16292225 | 0.81 | MAPK13 (0.85) | ALOX5NOX1MAPK11MAPK14MAPK13 | |
| SCHEMBL69095 | 0.81 | ALOX5 (0.78) | ALOX5MAPK11MAPK14MAPK13GCGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070112061-A1 | Heat- or singlet oxygen-generating agents and cancer treatment compositions comprising organic peroxide or chemiluminescent compound | MANAC INC. (JP) | 2007-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070112061-A1 | Heat- or singlet oxygen-generating agents and cancer treatment compositions comprising organic peroxide or chemiluminescent compound | HSPE1, MCL1, HMOX1 | ALOX5 378/4885NOX1 45/4885MAPK11 714/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.