Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | THRA | P10827 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1237860 | 0.80 | APLNR (0.58) | CNR2ALDH1A1TSHR | |
| SCHEMBL3905575 | 0.80 | APLNR (0.42) | ALDH1A1TSHRKDM4EHTT | |
| SCHEMBL16314448 | 0.79 | THRA (0.56) | THRATHRBNR5A1TSHRPLA2G4B | |
| SCHEMBL20237239 | 0.78 | CNR2 (0.58) | CNR1CNR2THRATHRBNR5A1 | |
| SCHEMBL19612480 | 0.77 | PLA2G4B (0.58) | THRATHRBNR5A1ALDH1A1TSHR | |
| SCHEMBL14223948 | 0.77 | CNR2 (0.39) | CNR2NR5A1KDM4E | |
| SCHEMBL13339091 | 0.76 | THRA (0.53) | CNR1CNR2THRATHRBNR5A1 | |
| SCHEMBL6132225 | 0.76 | ALDH1A1 (0.46) | THRBNR5A1ALDH1A1MEN1KMT2A | |
| SCHEMBL15396940 | 0.76 | ALDH1A1 (0.46) | THRBNR5A1ALDH1A1MEN1KMT2A | |
| SCHEMBL2846283 | 0.75 | MAPT (0.49) | CNR1CNR2THRATHRBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000071118-A1 | PHOSPHOLIPASE A2-SPECIFIC INHIBITING COMPOUNDS | UNIVERSITE PARIS 7 - DENIS DIDEROT (FR) | 2000-11-30 | — | — | WO | disclosed |