SCHEMBL2846283

SCHEMBL2846283

C=CCc1ccc(OCCCC)cc1OC

nearest known ligand 0.54

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.49
TDP1 Q9NUW8 1/20 0.49
CNR2 P34972 3/20 0.47
CNR1 P21554 2/20 0.45
THRA P10827 1/20 0.44
THRB P10828 1/20 0.44
AHR P35869 1/20 0.43
ALDH1A1 P00352 2/20 0.43
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2844393 0.94 TUBB4A (0.47) MAPTTDP1CNR2CNR1ALDH1A1
SCHEMBL2839058 0.91 CNR2 (0.52) MAPTTDP1CNR2CNR1ALDH1A1
SCHEMBL2842661 0.88 CNR2 (0.50) MAPTTDP1CNR2CNR1ALDH1A1
SCHEMBL2844258 0.88 CNR2 (0.50) MAPTTDP1CNR2CNR1AHR
SCHEMBL2848554 0.88 CNR2 (0.50) MAPTTDP1CNR2CNR1ALDH1A1
SCHEMBL2849927 0.88 CNR2 (0.47) MAPTTDP1CNR2CNR1ALDH1A1
SCHEMBL2841579 0.88 PTPN1 (0.49) MAPTTDP1CNR2AHRALDH1A1
SCHEMBL2839860 0.87 CNR2 (0.46) MAPTTDP1CNR2CNR1ALDH1A1
SCHEMBL2846352 0.85 CNR2 (0.50) MAPTTDP1CNR2CNR1ALDH1A1
SCHEMBL2844668 0.84 GABRA1 (0.46) MAPTTDP1CNR2CNR1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9497963-B2 Methods and compositions for control of gypsy moth, Lymantria dispar SIMON FRASER UNIVERSITY (CA) 2016-11-22 US disclosed
US-9125406-B2 Methods and compositions for control of cabbage looper, trichoplusia ni SIMON FRASER UNIVERSITY (CA) 2015-09-08 US disclosed
US-20130131185-A1 Methods and Compositions for Control of Cabbage Looper, Trichoplusia ni THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2013-05-23 US disclosed
US-20130045178-A1 METHODS AND COMPOSITIONS FOR CONTROL OF GYPSY MOTH, Lymantria dispar SIMON FRASER UNIVERSITY (CA) 2013-02-21 US disclosed
US-20100297059-A1 METHODS AND COMPOSITIONS FOR CONTROL OF GYPSY MOTHS, LYMANRIA DISPAR SIMON FRASER UNIVERSITY (CA) 2010-11-25 US disclosed
US-20100190865-A1 METHODS AND COMPOSITIONS FOR CONTROL OF GYPSY MOTHS, Lymanria dispar SIMON FRASER UNIVERSITY (CA) 2010-07-29 US disclosed
US-20100160451-A1 METHODS AND COMPOSITIONS FOR CONTROL OF CABBAGE LOOPER, Trichoplusia ni SIMON FRASER UNIVERSITY (CA) 2010-06-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130131185-A1 Methods and Compositions for Control of Cabbage Looper, Trichoplusia ni CDV3, ETV1, BOLA2; BOLA2B MAPT 4798/4885TDP1 3012/4885CNR2 56/4885
US-20130045178-A1 METHODS AND COMPOSITIONS FOR CONTROL OF GYPSY MOTH, Lymantria dispar L3MBTL3, L3MBTL4, L3MBTL1 MAPT 4810/4885TDP1 1624/4885CNR2 332/4885
US-20100190865-A1 METHODS AND COMPOSITIONS FOR CONTROL OF GYPSY MOTHS, Lymanria dispar L3MBTL3, L3MBTL4, L3MBTL1 MAPT 4813/4885TDP1 1252/4885CNR2 401/4885
US-20100160451-A1 METHODS AND COMPOSITIONS FOR CONTROL OF CABBAGE LOOPER, Trichoplusia ni CDV3, ETV1, TMSB4X MAPT 4792/4885TDP1 3110/4885CNR2 53/4885
US-20100297059-A1 METHODS AND COMPOSITIONS FOR CONTROL OF GYPSY MOTHS, LYMANRIA DISPAR L3MBTL3, L3MBTL4, L3MBTL1 MAPT 4820/4885TDP1 1255/4885CNR2 405/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.