Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 6/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | HPGDS | O60760 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 5/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ABL1 | P00519 | 2/20 | 0.42 |
| ▸ | GMNN | O75496 | 1/20 | 0.42 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | TUBB | P07437 | 1/20 | 0.42 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5983851 | 0.76 | FGFR1 (0.46) | HPGDHTTNPC1ALDH1A1MAPT | |
| SCHEMBL5981807 | 0.75 | KDM4E (0.49) | ALDH1A1SMN1; SMN2KDM4EKMT2A | |
| SCHEMBL5982863 | 0.72 | THRB (0.46) | HPGDMAPTRAB9ASMN1; SMN2MEN1 | |
| SCHEMBL10379900 | 0.71 | HPGD (0.47) | HPGDHTTHPGDSPTGS1PTGS2 | |
| SCHEMBL9482914 | 0.70 | NPC1 (0.49) | HPGDHTTHPGDSPTGS1PTGS2 | |
| SCHEMBL6793430 | 0.70 | HPGDS (0.83) | HPGDHTTHPGDSPTGS1PTGS2 | |
| SCHEMBL29615085 | 0.69 | HPGD (0.66) | HPGDHTTHPGDSPTGS1PTGS2 | |
| Carbamic Acid SCHEMBL3434151 | 0.69 | NPC1 (0.51) | HPGDHTTHPGDSPTGS1PTGS2 | |
| SCHEMBL5696324 | 0.68 | NPC1 (0.49) | HPGDHTTHPGDSPTGS1PTGS2 | |
| SCHEMBL1108963 | 0.68 | NPC1 (0.54) | HPGDHTTHPGDSPTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0980256-A2 | THE USE OF BIOLOGICALLY ACTIVE SUBSTANCES FOR INFLUENCING THE EXTRACELLULAR AREA OF SENSORY CELLS AND METHOD FOR CONTROLLING THE ADMINISTRATION OF ACTIVE SUBSTANCES AND DEVICE USED THEREIN | Eckmiller, Marion Sangster (DE) | 2000-02-23 | — | — | EP | disclosed |
| WO-1998050065-A2 | THE USE OF BIOLOGICALLY ACTIVE SUBSTANCES FOR INFLUENCING THE EXTRACELLULAR AREA OF SENSORY CELLS AND METHOD FOR CONTROLLING THE ADMINISTRATION OF ACTIVE SUBSTANCES AND DEVICE USED THEREIN | ECKMILLER MARION SANGSTER (DE) | 1998-11-12 | — | — | WO | disclosed |