SCHEMBL8033134

SCHEMBL8033134

NCC(=O)Nc1cccc2c(O)c(Cl)ccc12

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ GABRP O00591 2/20 0.44
▸ GABRD O14764 2/20 0.44
▸ GABRA1 P14867 2/20 0.44
▸ GABRB1 P18505 2/20 0.44
▸ GABRG2 P18507 2/20 0.44
▸ GABRB3 P28472 2/20 0.44
▸ GABRA5 P31644 2/20 0.44
▸ GABRA3 P34903 2/20 0.44
▸ GABRA2 P47869 2/20 0.44
▸ GABRB2 P47870 2/20 0.44
▸ GABRA4 P48169 2/20 0.44
▸ GABRE P78334 2/20 0.44
▸ GABRA6 Q16445 2/20 0.44
▸ GABRG1 Q8N1C3 2/20 0.44
▸ GABRG3 Q99928 2/20 0.44
▸ GABRQ Q9UN88 2/20 0.44
▸ MEN1 O00255 2/20 0.44
▸ KMT2A Q03164 2/20 0.44
▸ CA1 P00915 3/20 0.43
▸ CA2 P00918 3/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8029712 0.87 MEN1 (0.45) MEN1KMT2AALDH1A1POLBTRPV1
SCHEMBL8030052 0.84 GABRP (0.49) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL8029142 0.82 TSHR (0.51) ALDH1A1POLBTRPV1KDM4ELMNA
SCHEMBL20498063 0.81 TRPV1 (0.49) MEN1KMT2AALDH1A1TRPV1MAPT
SCHEMBL5351442 0.80 PARP14 (0.54) MEN1KMT2AALDH1A1POLBTRPV1
SCHEMBL8016606 0.80 ALDH1A1 (0.55) MEN1KMT2ACA1CA2ALDH1A1
SCHEMBL8016617 0.78 TRPV1 (0.43) MEN1KMT2AALDH1A1POLBTRPV1
SCHEMBL8017543 0.78 HPRT1 (0.50) MEN1KMT2AALDH1A1TRPV1MAPT
SCHEMBL8032326 0.75 GABRP (0.49) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL17501853 0.74 KDM4E (0.68) MEN1KMT2AALDH1A1POLBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0603954-B1 Immunoassay using a 4-hydroxy or 4-alkoxyarylacetamide as stabilizer JOHNSON & JOHNSON CLIN DIAG (US) 2000-03-08 — — EP disclosed
EP-0603953-B1 Use of 4' of 5'-hydroxy and 4'- or 5'-alkoxy-substituted electron transfer agents in compositions, elements, test kits and analytical methods JOHNSON & JOHNSON CLIN DIAG (US) 1999-02-17 — — EP disclosed
US-5736335-A Dry elements, test devices, test kits and methods for chemiluminescent detection of analytes using peroxidase-labeled reagents EASTMAN KODAK COMPANY (US) 1998-04-07 — — US disclosed
US-5641635-A Dry elements, test devices, test kits and methods for chemiluminescent detection of analytes using peroxidase-labeled reagents EASTMAN KODAK COMPANY (US) 1997-06-24 — — US disclosed
US-5372931-A Use of 4'-hydroxy- and 4'-alkoxy-substituted electron transfer agents in compositions, elements, test kits and analytical methods EASTMAN KODAK COMPANY (US) 1994-12-13 — — US disclosed
US-5372932-A Peroxidase-labeled immunoreactant; stabiliztion with a 4-hydroxy or 4-alkoxyarylacetamide EASTMAN KODAK COMPANY (US) 1994-12-13 — — US disclosed
EP-0603953-A1 Use of 4' of 5'-hydroxy and 4'- or 5'-alkoxy-substituted electron transfer agents in compositions, elements, test kits and analytical methods Johnson & Johnson Clinical Diagnostics, Inc. (US) 1994-06-29 — — EP disclosed
EP-0603954-A2 Analytical element and immunoassay using a 4-hydroxy or 4-alkoxyarylacetamide as stabilizer Johnson & Johnson Clinical Diagnostics, Inc. (US) 1994-06-29 — — EP disclosed
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