Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | EEF2K | O00418 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8035741 | 0.81 | ALDH1A1 (0.54) | PPARGALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL8033268 | 0.81 | KDM4E (0.45) | PPARGALDH1A1KMT2AMEN1FAAH | |
| SCHEMBL8033227 | 0.79 | ALDH1A1 (0.59) | PPARGALDH1A1SMN1; SMN2SIGMAR1KMT2A | |
| SCHEMBL8035752 | 0.79 | PPARA (0.55) | ALDH1A1SMN1; SMN2SIGMAR1KMT2AMEN1 | |
| SCHEMBL8020077 | 0.78 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2KMT2AMEN1FAAH | |
| SCHEMBL8029589 | 0.78 | TSHR (0.61) | ALDH1A1SMN1; SMN2KMT2AMEN1FAAH | |
| Hydrochloric Acid SCHEMBL8887455 | 0.77 | TSHR (0.60) | ALDH1A1SMN1; SMN2KMT2AMEN1FAAH | |
| SCHEMBL8910223 | 0.74 | KMT2A (0.61) | ALDH1A1SMN1; SMN2SIGMAR1KMT2AMEN1 | |
| SCHEMBL5064012 | 0.74 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2SIGMAR1KMT2AMEN1 | |
| SCHEMBL8033255 | 0.74 | SMN1; SMN2 (0.56) | ALDH1A1SMN1; SMN2KMT2AMEN1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0702010-B1 | Benzopyranderivatives, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2000-03-15 | — | — | EP | disclosed |
| US-5668138-A | AFFINITY FOR SIGMA RECEPTORS, CENTRAL NERVOUS SYSTEM DISORDERS | ADIR ET COMPAGNIE (FR) | 1997-09-16 | — | — | US | disclosed |