Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8020077 | 0.82 | ALDH1A1 (0.50) | SMN1; SMN2ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL8029589 | 0.82 | TSHR (0.61) | SMN1; SMN2ALDH1A1MEN1KMT2ALMNA | |
| Hydrochloric Acid SCHEMBL8887455 | 0.81 | TSHR (0.60) | SMN1; SMN2ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL25295840 | 0.81 | ALDH1A1 (0.59) | PPARANPC1RAB9ARXFP1SMN1; SMN2 | |
| SCHEMBL8033345 | 0.79 | PPARG (0.48) | SMN1; SMN2ALDH1A1SIGMAR1MEN1KMT2A | |
| SCHEMBL8035809 | 0.79 | SIGMAR1 (0.53) | PPARAALDH1A1SIGMAR1KMT2ALMNA | |
| SCHEMBL5064012 | 0.78 | ALDH1A1 (0.56) | SMN1; SMN2ALDH1A1SIGMAR1MEN1KMT2A | |
| SCHEMBL8033255 | 0.78 | SMN1; SMN2 (0.56) | SMN1; SMN2ALDH1A1MEN1KMT2APOLB | |
| SCHEMBL8035824 | 0.77 | SMN1; SMN2 (0.52) | SMN1; SMN2ALDH1A1SIGMAR1MEN1KMT2A | |
| SCHEMBL8887841 | 0.77 | PPARA (0.48) | PPARASIGMAR1MEN1KMT2APTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0702010-B1 | Benzopyranderivatives, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2000-03-15 | — | — | EP | disclosed |
| US-5691340-A | CENTRAL NERVOUS SYSTEM DISORDERS, STROKES, CARDIOVASCULAR DISORDERS, ALZHEIMER*S DISEASE OR ANTIINFLAMMATORY AGENTS | ADIR ET COMPAGNIE (FR) | 1997-11-25 | — | — | US | disclosed |
| US-5668138-A | AFFINITY FOR SIGMA RECEPTORS, CENTRAL NERVOUS SYSTEM DISORDERS | ADIR ET COMPAGNIE (FR) | 1997-09-16 | — | — | US | disclosed |
| EP-0702010-A1 | Benzopyranderivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1996-03-20 | — | — | EP | disclosed |