Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | FAAH | O00519 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8035824 | 0.85 | SMN1; SMN2 (0.52) | ALDH1A1SMN1; SMN2KMT2AMEN1FAAH | |
| SCHEMBL8035752 | 0.82 | PPARA (0.55) | ALDH1A1SMN1; SMN2KMT2AMEN1FAAH | |
| SCHEMBL8029589 | 0.81 | TSHR (0.61) | ALDH1A1SMN1; SMN2KMT2AMEN1FAAH | |
| Hydrochloric Acid SCHEMBL8887455 | 0.80 | TSHR (0.60) | ALDH1A1SMN1; SMN2KMT2AMEN1FAAH | |
| SCHEMBL8020090 | 0.79 | SIGMAR1 (0.42) | ALDH1A1SMN1; SMN2KMT2AMEN1MAPK1 | |
| SCHEMBL8033345 | 0.78 | PPARG (0.48) | ALDH1A1SMN1; SMN2KMT2AMEN1FAAH | |
| SCHEMBL5064012 | 0.77 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2KMT2AMEN1TSHR | |
| SCHEMBL8033255 | 0.77 | SMN1; SMN2 (0.56) | ALDH1A1SMN1; SMN2KMT2AMEN1FAAH | |
| SCHEMBL8035741 | 0.76 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2KMT2AMEN1FAAH | |
| SCHEMBL8020104 | 0.76 | LMNA (0.59) | ALDH1A1SMN1; SMN2KMT2AMEN1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0702010-B1 | Benzopyranderivatives, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2000-03-15 | — | — | EP | disclosed |
| US-5691340-A | CENTRAL NERVOUS SYSTEM DISORDERS, STROKES, CARDIOVASCULAR DISORDERS, ALZHEIMER*S DISEASE OR ANTIINFLAMMATORY AGENTS | ADIR ET COMPAGNIE (FR) | 1997-11-25 | — | — | US | disclosed |
| US-5668138-A | AFFINITY FOR SIGMA RECEPTORS, CENTRAL NERVOUS SYSTEM DISORDERS | ADIR ET COMPAGNIE (FR) | 1997-09-16 | — | — | US | disclosed |
| EP-0702010-A1 | Benzopyranderivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1996-03-20 | — | — | EP | disclosed |