SCHEMBL8033501

SCHEMBL8033501

CCCCN(c1ccc(SC)cc1)C(C)C(=O)O.[NaH]

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 3/20 0.38
AKR1C2 P52895 3/20 0.38
TAS1R3 Q7RTX0 1/20 0.37
TAS1R1 Q7RTX1 1/20 0.37
FPR2 P25090 1/20 0.36
NOX1 Q9Y5S8 1/20 0.35
MLYCD O95822 1/20 0.34
SLC6A4 P31645 1/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
MMP2 P08253 2/20 0.33
CNR2 P34972 1/20 0.33
KIF11 P52732 1/20 0.33
MMP9 P14780 1/20 0.33
TACR1 P25103 1/20 0.33
ALDH1A1 P00352 3/20 0.33
MMP3 P08254 1/20 0.33
ADRB2 P07550 1/20 0.33
TSHR P16473 1/20 0.33
ACE P12821 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8033504 0.85 TAS1R3 (0.36) AKR1C3AKR1C2TAS1R3TAS1R1NOX1
SCHEMBL6555714 0.84 ALDH1A1 (0.37) TAS1R3TAS1R1NOX1MLYCDSLC6A4
SCHEMBL6555711 0.84 ALDH1A1 (0.37) TAS1R3TAS1R1NOX1MLYCDSLC6A4
SCHEMBL3342832 0.82 ALDH1A1 (0.45) CNR2TACR1ALDH1A1MMP3ADRB2
SCHEMBL3342836 0.82 ALDH1A1 (0.45) CNR2TACR1ALDH1A1MMP3ADRB2
SCHEMBL6555727 0.81 CNR2 (0.40) MLYCDKMT2AMMP2CNR2MMP9
SCHEMBL6555751 0.81 ALOX5 (0.46) MEN1KMT2AALDH1A1TSHR
SCHEMBL6555724 0.81 CNR2 (0.40) MLYCDKMT2AMMP2CNR2MMP9
SCHEMBL6555754 0.81 ALOX5 (0.46) MEN1KMT2AALDH1A1TSHR
SCHEMBL10782208 0.78 NPC1 (0.50) CNR2TACR1ALDH1A1MMP3ADRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0786690-B1 Silver halide light sensitive emulsion layer having enhanced photographic sensitivity EASTMAN KODAK CO (US) 2000-03-22 EP disclosed
US-5747235-A SILVER HALIDE ADSORBERS IN EMULSIONS FOR PHOTOGRAPHIC FILMS EASTMAN KODAK COMPANY (US) 1998-05-05 US disclosed
EP-0786690-A2 Silver halide light sensitive emulsion layer having enhanced photographic sensitivity EASTMAN KODAK COMPANY (US) 1997-07-30 EP disclosed