Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 4/20 | 0.33 |
| ▸ | CCR3 | P51677 | 1/20 | 0.32 |
| ▸ | BDKRB2 | P30411 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.32 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.31 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.31 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8030021 | 0.91 | KMT2A (0.35) | MEN1GAAKMT2ACCR3SMN1; SMN2 | |
| SCHEMBL8030193 | 0.90 | SMN1; SMN2 (0.33) | MEN1GAAKMT2ACCR3BDKRB2 | |
| SCHEMBL8030140 | 0.89 | CASR (0.34) | CCR3BDKRB2CXCR1CXCR2 | |
| SCHEMBL27489407 | 0.89 | CASR (0.33) | CCR3BDKRB2CXCR1CXCR2 | |
| SCHEMBL8034072 | 0.88 | BDKRB2 (0.40) | BDKRB2SMN1; SMN2NR1H4CXCR1CXCR2 | |
| SCHEMBL8020616 | 0.87 | CASR (0.42) | MEN1KMT2ABDKRB2SMN1; SMN2 | |
| SCHEMBL8020575 | 0.86 | CASR (0.35) | MEN1GAAKMT2ACXCR1CXCR2 | |
| SCHEMBL8020116 | 0.86 | KMT2A (0.36) | MEN1GAAKMT2ACCR3SMN1; SMN2 | |
| SCHEMBL8030295 | 0.85 | KMT2A (0.34) | MEN1GAAKMT2ACCR3SMN1; SMN2 | |
| SCHEMBL8020566 | 0.84 | MEN1 (0.34) | MEN1GAAKMT2ACCR3BDKRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0985660-A1 | AMINOPHENOL DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2000-03-15 | — | — | EP | disclosed |
| CN-1178523-A | Aminophenol derivatives | DIICHI PHARMACEUTICAL CO LTD (JP) | 1998-04-08 | — | — | CN | disclosed |