Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | PPIA | P62937 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | BDKRB2 | P30411 | 6/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8034072 | 0.93 | BDKRB2 (0.40) | CASRRAB9AMAPTSMN1; SMN2PPIA | |
| SCHEMBL8033741 | 0.93 | CASR (0.46) | CASRRAB9AMEN1KMT2AMAPT | |
| SCHEMBL8030233 | 0.91 | CASR (0.41) | CASRRAB9AMEN1KMT2AMAPT | |
| SCHEMBL8020760 | 0.90 | CASR (0.42) | CASRRAB9AMEN1KMT2AMAPT | |
| SCHEMBL8030193 | 0.88 | SMN1; SMN2 (0.33) | CASRRAB9AMEN1KMT2AMAPT | |
| SCHEMBL8020713 | 0.88 | CASR (0.44) | CASRRAB9AMEN1KMT2AMAPT | |
| SCHEMBL8030021 | 0.88 | KMT2A (0.35) | CASRMEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL8020575 | 0.88 | CASR (0.35) | CASRMEN1KMT2A | |
| SCHEMBL8030224 | 0.87 | CASR (0.45) | CASRRAB9AMEN1KMT2AMAPT | |
| SCHEMBL8033877 | 0.87 | MEN1 (0.33) | MEN1KMT2ASMN1; SMN2BDKRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0985660-A1 | AMINOPHENOL DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2000-03-15 | — | — | EP | disclosed |