Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8051249 | 0.78 | RAB9A (0.35) | ALDH1A1NPC1RAB9AKDM4EHPGD | |
| SCHEMBL8033786 | 0.77 | MAPT (0.39) | KMT2AALDH1A1NPC1HPGDLMNA | |
| SCHEMBL8043035 | 0.77 | MAPT (0.33) | ALDH1A1KDM4ELMNA | |
| SCHEMBL8033964 | 0.77 | SMN1; SMN2 (0.39) | MEN1KMT2AL3MBTL1ALDH1A1NPC1 | |
| SCHEMBL8037035 | 0.76 | CYP1A2 (0.34) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL8033927 | 0.75 | NPSR1 (0.40) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL8043982 | 0.74 | ALDH1A1 (0.47) | MEN1KMT2AL3MBTL1ALDH1A1HPGD | |
| SCHEMBL8032416 | 0.73 | ALDH1A1 (0.43) | MEN1KMT2AL3MBTL1ALDH1A1NPC1 | |
| SCHEMBL8043960 | 0.73 | L3MBTL1 (0.51) | MEN1KMT2AL3MBTL1ALDH1A1NPC1 | |
| SCHEMBL8042051 | 0.73 | MEN1 (0.41) | MEN1KMT2AL3MBTL1ALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |