Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.40 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.40 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.40 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8034242 | 0.83 | HPGD (0.47) | HPGDALDH1A1KDM4EGLAPOLB | |
| SCHEMBL10786550 | 0.77 | CACNA1F (0.53) | HPGDALDH1A1KDM4EGLAPOLB | |
| SCHEMBL8563432 | 0.75 | ABCC1 (0.46) | HPGDALDH1A1KDM4EGLAPOLB | |
| SCHEMBL9691059 | 0.71 | CACNA1F (0.50) | HPGDALDH1A1KDM4EGLAPOLB | |
| SCHEMBL8396236 | 0.70 | ALDH1A1 (0.54) | HPGDALDH1A1KDM4EHSD17B10NPSR1 | |
| SCHEMBL8437311 | 0.69 | CACNA1F (0.51) | HPGDALDH1A1KDM4EGLAPOLB | |
| SCHEMBL8438113 | 0.69 | HPGD (0.60) | HPGDALDH1A1KDM4EGLAPOLB | |
| SCHEMBL8468645 | 0.68 | HPGD (0.43) | HPGDALDH1A1KDM4EGLAPOLB | |
| SCHEMBL8319383 | 0.67 | HPGD (0.43) | HPGDALDH1A1KDM4EGLAPOLB | |
| SCHEMBL1598439 | 0.66 | KMT2A (0.53) | HPGDALDH1A1HSD17B10SMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0758648-B1 | Substituted 4H-pyrans with a modulating effect on calcium channels | BAYER AG (DE) | 2000-03-15 | — | — | EP | disclosed |
| EP-0758648-A1 | Substituted 4H-pyrans with a modulating effect on calcium channels | BAYER AG (DE) | 1997-02-19 | — | — | EP | disclosed |