Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC1 | P33527 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.39 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.39 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.39 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8562368 | 0.78 | HPGD (0.46) | ABCC1HPGDNPSR1SMN1; SMN2KDM4E | |
| SCHEMBL10830868 | 0.77 | ABCC1 (0.52) | ABCC1HPGDNPSR1SMN1; SMN2KDM4E | |
| SCHEMBL8034212 | 0.75 | HPGD (0.43) | ABCC1HPGDNPSR1SMN1; SMN2KDM4E | |
| SCHEMBL9312804 | 0.71 | ABCC1 (0.65) | ABCC1HPGDNPSR1SMN1; SMN2KDM4E | |
| SCHEMBL9217592 | 0.70 | NPSR1 (0.69) | ABCC1HPGDNPSR1SMN1; SMN2KDM4E | |
| SCHEMBL8561209 | 0.68 | ABCC1 (0.63) | ABCC1HPGDNPSR1SMN1; SMN2KDM4E | |
| SCHEMBL8040446 | 0.68 | KDM4E (0.46) | ABCC1HPGDNPSR1SMN1; SMN2KDM4E | |
| SCHEMBL27363828 | 0.68 | ABCC1 (0.46) | ABCC1HPGDNPSR1SMN1; SMN2KDM4E | |
| SCHEMBL8562068 | 0.68 | HPGD (0.66) | ABCC1HPGDNPSR1SMN1; SMN2KDM4E | |
| SCHEMBL8558368 | 0.65 | KDM4E (0.47) | ABCC1HPGDNPSR1SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5760073-A | TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS | BAYER AKTIENGESELLSCHAFT (DE) | 1998-06-02 | — | — | US | disclosed |