SCHEMBL8034262

SCHEMBL8034262

CS(=O)(=O)c1cccc2[nH]c(S)nc12

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 1/20 0.37
PTGS2 P35354 1/20 0.37
NPC1 O15118 1/20 0.34
RAB9A P51151 1/20 0.34
KMT2A Q03164 1/20 0.34
PARP1 P09874 4/20 0.33
DRD4 P21917 1/20 0.32
ATR Q13535 1/20 0.32
ALOX5 P09917 1/20 0.32
KDM4E B2RXH2 2/20 0.32
HPGD P15428 1/20 0.32
ESR1 P03372 1/20 0.32
JAK2 O60674 1/20 0.31
JAK3 P52333 1/20 0.31
PTK2 Q05397 1/20 0.31
DHODH Q02127 1/20 0.31
ALOX12 P18054 1/20 0.31
GAA P10253 1/20 0.31
MAPT P10636 1/20 0.31
MAPK1 P28482 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL989259 0.83 L3MBTL1 (0.40) PARP1KDM4EHPGDDHODHALOX12
Silver SCHEMBL9320049 0.82 PARP1 (0.33) PARP1KDM4EHPGDDHODH
SCHEMBL11327139 0.82 DUSP5 (0.35) PARP1KDM4EHPGDDHODH
SCHEMBL8712895 0.79 FEN1 (0.41) KMT2AKDM4EGAAMAPT
SCHEMBL7451781 0.76 DRD4 (0.37) PTGS1PTGS2NPC1RAB9AKMT2A
SCHEMBL5859159 0.76 KDM4E (0.39) PTGS1PTGS2NPC1RAB9AKMT2A
SCHEMBL9434820 0.75 CHEK1 (0.39) KMT2ADRD4KDM4EHPGDMAPT
SCHEMBL8034264 0.73 NPC1 (0.34) PTGS1PTGS2NPC1RAB9AKMT2A
SCHEMBL110724 0.73 MGAM (0.53) ESR1GAA
SCHEMBL31547353 0.73 MGAM (0.53) ESR1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0983316-A1 A POLYMERIC COMPOSITE MATERIAL WITH IMPROVED FLAME RESISTANCE Duslo, a.s. Sal'a (SK) 2000-03-08 EP disclosed
WO-1998046673-A1 A POLYMERIC COMPOSITE MATERIAL WITH IMPROVED FLAME RESISTANCE DUSLO, A.S. S^¿ALA (SK) 1998-10-22 WO disclosed