SCHEMBL8034264

SCHEMBL8034264

CS(=O)(=O)c1cccc2nc(S)[nH]c12

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.34
RAB9A P51151 1/20 0.34
KMT2A Q03164 1/20 0.34
DRD4 P21917 1/20 0.32
PABPC1 P11940 1/20 0.32
EIF4H Q15056 1/20 0.32
JAK2 O60674 1/20 0.31
JAK3 P52333 1/20 0.31
PTK2 Q05397 1/20 0.31
PTGS1 P23219 1/20 0.31
PTGS2 P35354 1/20 0.31
ALOX12 P18054 1/20 0.31
ALDH1A1 P00352 2/20 0.31
HPGD P15428 1/20 0.31
NR3C1 P04150 1/20 0.31
PGR P06401 1/20 0.31
NR3C2 P08235 1/20 0.31
AR P10275 1/20 0.31
NPBWR1 P48145 1/20 0.31
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8999607 0.83 L3MBTL1 (0.40) ALOX12L3MBTL1
SCHEMBL5859162 0.76 KDM4E (0.39) NPC1RAB9AKMT2ADRD4ALDH1A1
SCHEMBL2581908 0.75 PARP1 (0.42) NPC1RAB9AKMT2ADRD4ALOX12
SCHEMBL2509772 0.75 PARP1 (0.42) NPC1RAB9AKMT2ADRD4ALOX12
SCHEMBL8034262 0.73 PTGS1 (0.37) NPC1RAB9AKMT2ADRD4JAK2
SCHEMBL110725 0.73 ALDH1A1 (0.41) NPC1RAB9AALDH1A1HPGDAR
SCHEMBL9306189 0.72 KIF11 (0.42) ALDH1A1
SCHEMBL10835916 0.72 DAO (0.41) RAB9AKMT2AALDH1A1
SCHEMBL28412208 0.72 PSMD14 (0.33) NPC1RAB9AALDH1A1POLB
SCHEMBL1524362 0.72 ALDH1A1 (0.40) NPC1RAB9AALDH1A1HPGDAR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0983316-A1 A POLYMERIC COMPOSITE MATERIAL WITH IMPROVED FLAME RESISTANCE Duslo, a.s. Sal'a (SK) 2000-03-08 EP disclosed
WO-1998046673-A1 A POLYMERIC COMPOSITE MATERIAL WITH IMPROVED FLAME RESISTANCE DUSLO, A.S. S^¿ALA (SK) 1998-10-22 WO disclosed