SCHEMBL8034267

SCHEMBL8034267

C[Si](C)(CCCN)O[SiH2]CCN

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2236671 0.93
SCHEMBL9685081 0.86
SCHEMBL5393817 0.83 DNM1 (0.41)
SCHEMBL5383782 0.83
SCHEMBL4392722 0.77
SCHEMBL2030789 0.72 NFKB1 (0.30)
SCHEMBL5389406 0.71 MAOA (0.39)
SCHEMBL126890 0.71 NFKB1 (0.33)
SCHEMBL13647426 0.70
SCHEMBL7562867 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119285962-A Preparation method of acrylic ester modified block silicone oil 湖北兴瑞硅材料有限公司 2025-01-10 CN disclosed
CN-111004395-B Preparation method of low-solvent block type polyether amino silicone oil 浙江理工大学桐乡研究院有限公司 2021-12-14 CN disclosed
CN-111004395-A Preparation method of low-solvent block type polyether amino silicone oil 浙江理工大学桐乡研究院有限公司 2020-04-14 CN disclosed
CN-102617863-A Preparation method of hydrophilic block polyether aminosilicone UNIV GUANGDONG TECHNOLOGY 2012-08-01 CN disclosed
CN-101784584-B Organopolysiloxanes having polyhydroxyamido groups and preparation thereof WACKER CHEMIE AG 2012-07-04 CN disclosed
CN-101784584-A Organopolysiloxanes having polyhydroxyamido groups and preparation thereof WACKER CHEMIE AG 2010-07-21 CN disclosed
CN-100404622-C Crosslinkable polyorganosiloxane compositions WACKER CHEMIE AG (DE) 2008-07-23 CN disclosed
CN-1789339-A Crosslinkable polyorganosiloxane compositions WACKER CHEMIE AG (DE) 2006-06-21 CN disclosed
CN-1079867-C Tissue products containing softeners and silicone glycol KIMBERLY CLARK CO (US) 2002-02-27 CN disclosed
US-6040365-A Finished swimming caps, and compositions and methods for producing same THEDERS JOHN B (US) 2000-03-21 US disclosed
US-5925418-A Finishing swimming caps, and compositions and methods for producing same THEDERS JOHN B (US) 1999-07-20 US disclosed
CN-1202946-A Tissue paper products containing softening agents and silicone glycols KIMBERLY CLARK CO (US) 1998-12-23 CN disclosed
US-5724671-A Finished swimming caps, and compositions and methods for producing same THEDERS JOHN B (US) 1998-03-10 US disclosed
WO-1998002212-A2 FINISHED SWIMMING CAPS, AND COMPOSITIONS AND METHODS FOR PRODUCING SAME THEDERS JOHN B (US) 1998-01-22 WO disclosed