Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 3/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.41 |
| ▸ | APP | P05067 | 3/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.34 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.34 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.34 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.34 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.34 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 2/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.34 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.33 |
| ▸ | CASR | P41180 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8049037 | 0.87 | KIF11 (0.38) | AKR1C3AKR1C2KIF11 | |
| SCHEMBL8044840 | 0.87 | AKR1C3 (0.33) | AKR1C3AKR1C2GRM2 | |
| SCHEMBL8034747 | 0.87 | MAOB (0.36) | AKR1C3AKR1C2APPMAOBKCNH2 | |
| SCHEMBL8567647 | 0.86 | MAOB (0.45) | MAOBKIF11KCNH2TMEM97 | |
| SCHEMBL8043786 | 0.86 | AKR1C3 (0.42) | AKR1C3AKR1C2APPMAOBKIF11 | |
| SCHEMBL8044843 | 0.85 | AKR1C3 (0.41) | AKR1C3AKR1C2APPKIF11TMEM97 | |
| SCHEMBL8563691 | 0.81 | MAOB (0.45) | MAOBKCNH2TMEM97 | |
| SCHEMBL8046024 | 0.80 | GPR84 (0.37) | MAOBKIF11GRM2 | |
| SCHEMBL10786215 | 0.79 | RARB (0.35) | APPMAOBGRM2 | |
| SCHEMBL8044464 | 0.79 | DAO (0.36) | KIF11MDM2PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0733692-B1 | Liquid crystalline compound, liquid crystal composition containing the same, and display device | CHISSO CORP (JP) | 2000-06-14 | — | — | EP | disclosed |
| US-5714088-A | TRIFLUOROMETHYL- OR -METHOXYPHENYL-SUBSTITUTED BRANCHED ALKYL-SUBSTITUTED CYCLOHEXANES; LARGE POSITIVE VALUE OF DIELECTRIC ANISOTROPY; VERY LOW VISCOSITY; HIGH VOLTAGE HOLDING RATIO(SPECIFIC RESISTANCE); UV STABILITY | CHISSO CORPORATION (JP) | 1998-02-03 | — | — | US | disclosed |
| EP-0733692-A1 | Liquid crystalline compound, liquid crystal composition containing the same, and display device | Chisso Corporation (JP) | 1996-09-25 | — | — | EP | disclosed |