Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11139530 | 0.82 | CYP3A4 (0.47) | TDP1CYP3A4ALDH1A1THRBALOX15 | |
| SCHEMBL8036589 | 0.81 | PKM (0.40) | TDP1CYP3A4ALDH1A1THRBALOX15 | |
| SCHEMBL5888492 | 0.81 | ALDH1A1 (0.41) | TDP1CYP3A4ALDH1A1THRBALOX15 | |
| SCHEMBL4854335 | 0.80 | ALDH1A1 (0.46) | TDP1CYP3A4ALDH1A1THRBALOX15 | |
| SCHEMBL8024990 | 0.78 | ALDH1A1 (0.37) | TDP1CYP3A4ALDH1A1THRBALOX15 | |
| SCHEMBL4880809 | 0.77 | ALOX15 (0.39) | TDP1CYP3A4ALDH1A1THRBALOX15 | |
| SCHEMBL8040807 | 0.77 | CYP3A4 (0.41) | TDP1CYP3A4ALDH1A1THRBALOX15 | |
| SCHEMBL3863727 | 0.75 | ALDH1A1 (0.50) | TDP1CYP3A4ALDH1A1THRBALOX15 | |
| SCHEMBL9297193 | 0.74 | TAS1R3 (0.41) | TDP1CYP3A4ALDH1A1THRBALOX15 | |
| Hydrochloric Acid SCHEMBL3858550 | 0.73 | ALDH1A1 (0.49) | TDP1CYP3A4ALDH1A1THRBALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6024769-A | HAIR COLORS AND HAIR DYEING; RESISTANCE TO LIGHT, WASHINGS, PERSPIRATION AND ADVERSE WEATHER | L'OREAL (FR) | 2000-02-15 | — | — | US | claimed |
| EP-0663814-B1 | PROCESS FOR DYEING KERATIN FIBRES USING AN ACID PH ALCOXYMETEPHENYLENEDIAMINE AND COMPOSITIONS THEREFOR | OREAL (FR) | 1999-04-28 | — | — | EP | claimed |
| EP-0424261-B1 | Dyeing composition containing oxidation dyes precursors and aminoindole derivatives as coupling agent | OREAL (FR) | 1996-01-03 | — | — | EP | claimed |
| US-5279620-A | Containg paraphenylenediamine, para-aminophenol and paraheterocyclic precursors | L'OREAL (FR) | 1994-01-18 | — | — | US | claimed |
| US-6024769-A | HAIR COLORS AND HAIR DYEING; RESISTANCE TO LIGHT, WASHINGS, PERSPIRATION AND ADVERSE WEATHER | L'OREAL (FR) | 2000-02-15 | — | — | US | disclosed |
| US-5364414-A | Hair dyes or oxidation color dyes | L'OREAL (FR) | 1994-11-15 | — | — | US | disclosed |
| US-5279620-A | Containg paraphenylenediamine, para-aminophenol and paraheterocyclic precursors | L'OREAL (FR) | 1994-01-18 | — | — | US | disclosed |