Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STS | P08842 | 12/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.72 |
| ▸ | CA1 | P00915 | 2/20 | 0.72 |
| ▸ | CA2 | P00918 | 2/20 | 0.72 |
| ▸ | CA9 | Q16790 | 2/20 | 0.72 |
| ▸ | ESR1 | P03372 | 2/20 | 0.72 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.72 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.72 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.72 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.72 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.72 |
| ▸ | CA4 | P22748 | 1/20 | 0.72 |
| ▸ | CA6 | P23280 | 1/20 | 0.72 |
| ▸ | LMNA | P02545 | 2/20 | 0.68 |
| ▸ | MAPT | P10636 | 2/20 | 0.68 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.68 |
| ▸ | RECQL | P46063 | 1/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8034634 | 0.91 | STS (0.79) | STSKDM4ECA1CA2CA9 | |
| SCHEMBL10134113 | 0.87 | HSD17B1 (0.74) | STSKDM4ECA1CA2CA9 | |
| SCHEMBL6691697 | 0.87 | HSD17B1 (0.74) | STSKDM4ECA1CA2CA9 | |
| SCHEMBL21067318 | 0.86 | STS (0.84) | STSKDM4ECA1CA2CA9 | |
| SCHEMBL8034430 | 0.85 | STS (0.82) | STSKDM4ECA1CA2CA9 | |
| SCHEMBL17531381 | 0.85 | STS (0.82) | STSKDM4ECA1CA2CA9 | |
| Estrone Sulfuric Acid SCHEMBL12920398 | 0.84 | STS (1.00) | STSKDM4ECA1CA2CA9 | |
| Emate SCHEMBL14548146 | 0.84 | STS (1.00) | STSKDM4ECA1CA2CA9 | |
| Estrone Sulfuric Acid SCHEMBL22846 | 0.84 | STS (1.00) | STSKDM4ECA1CA2CA9 | |
| SCHEMBL21034361 | 0.84 | STS (0.80) | STSKDM4ECA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0602123-B1 | STEROID SULPHATASE INHIBITORS | STERIX LTD (GB) | 2000-03-29 | — | — | EP | claimed |
| WO-1993005063-A1 | STEROID SULPHATASE INHIBITORS | IMPERIAL COLLEGE OF SCIENCE, TECHNOLOGY AND MEDICINE (GB) | 1993-03-18 | — | — | WO | claimed |
| EP-0602123-B1 | STEROID SULPHATASE INHIBITORS | STERIX LTD (GB) | 2000-03-29 | — | — | EP | disclosed |
| WO-1997008187-A1 | N-BUTYLSULFONATE ESTERS OF ESTROGENS | ELI LILLY AND COMPANY (US) | 1997-03-06 | — | — | WO | disclosed |