Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 5/20 | 0.34 |
| ▸ | CA1 | P00915 | 4/20 | 0.34 |
| ▸ | CA2 | P00918 | 4/20 | 0.34 |
| ▸ | CA9 | Q16790 | 4/20 | 0.34 |
| ▸ | CA7 | P43166 | 3/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.31 |
| ▸ | ALPL | P05186 | 1/20 | 0.31 |
| ▸ | CA6 | P23280 | 2/20 | 0.31 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.31 |
| ▸ | CA3 | P07451 | 1/20 | 0.31 |
| ▸ | TYR | P14679 | 1/20 | 0.31 |
| ▸ | DRD1 | P21728 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28389785 | 0.67 | ALDH1A1 (0.51) | ALDH1A1LMNAALOX5HSD17B10ESR2 | |
| SCHEMBL28705640 | 0.63 | ALDH1A1 (0.45) | ALDH1A1LMNAESR2HSD17B1AKR1B1 | |
| SCHEMBL11427495 | 0.63 | ALDH1A1 (0.42) | ALDH1A1LMNACA12CA1CA2 | |
| SCHEMBL27501961 | 0.61 | ALDH1A1 (0.50) | ALDH1A1LMNAESR2HSD17B1DRD1 | |
| SCHEMBL30489960 | 0.60 | ALDH1A1 (0.66) | ALDH1A1LMNAALOX5DRD1MEN1 | |
| SCHEMBL8359447 | 0.58 | PDE3B (0.41) | ALDH1A1CA12CA1CA2CA9 | |
| SCHEMBL8038664 | 0.57 | DRD2 (0.33) | ALDH1A1LMNAHSD17B10ESR2DRD1 | |
| SCHEMBL26125144 | 0.57 | ESR2 (0.41) | ALDH1A1LMNATSHRHSD17B10ESR2 | |
| SCHEMBL27841256 | 0.57 | ALOX5 (0.44) | ALDH1A1LMNACA12CA1CA2 | |
| SCHEMBL577820 | 0.56 | DRD2 (0.41) | HSD17B10ESR2HSD17B1DRD1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0661039-B1 | Oxidative hair dyeing method, composition and kit utilizing hydroxyl substituted benzothiazines | BRISTOL MYERS SQUIBB CO (US) | 2000-04-05 | — | — | EP | disclosed |
| EP-0661039-A1 | Oxidative hair dyeing method, composition and kit utilizing hydroxyl substituted benzothiazines | Bristol-Myers Squibb Company (US) | 1995-07-05 | — | — | EP | disclosed |
| US-5374288-A | Oxidative hair dyeing method, composition, and kit utilizing hydroxyl substituted benzothiazines | CLAIROL INCORPORATED (US) | 1994-12-20 | — | — | US | disclosed |