Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 1/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 4/20 | 0.37 |
| ▸ | CA1 | P00915 | 4/20 | 0.37 |
| ▸ | CA2 | P00918 | 4/20 | 0.37 |
| ▸ | CA9 | Q16790 | 4/20 | 0.37 |
| ▸ | CA7 | P43166 | 3/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.37 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8359449 | 0.84 | SRD5A1 (0.42) | PDE3BPDE3ACA1CA2ALDH1A1 | |
| SCHEMBL8359371 | 0.82 | ALDH1A1 (0.46) | CA12CA1CA2CA9CA7 | |
| SCHEMBL8359369 | 0.78 | NAMPT (0.35) | CA12CA1CA2CA9CA7 | |
| SCHEMBL515808 | 0.76 | TRPA1 (0.44) | ALDH1A1TSHRMEN1POLBKMT2A | |
| SCHEMBL12941012 | 0.72 | PDE3B (0.41) | PDE3BPDE3AESR2HSD17B1ESR1 | |
| SCHEMBL12652383 | 0.69 | PDE3B (0.39) | PDE3BPDE3ACA12CA2CA9 | |
| SCHEMBL7876604 | 0.66 | PDE3B (0.43) | PDE3BPDE3AESR2ESR1MAOA | |
| SCHEMBL4373834 | 0.66 | PDE3B (0.39) | PDE3BPDE3AHSD17B1DRD1TYR | |
| SCHEMBL12471893 | 0.64 | ESR2 (0.40) | CA12CA1CA2CA9CA7 | |
| SCHEMBL29722944 | 0.63 | PDE3B (0.37) | PDE3BPDE3AALDH1A1TSHRESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003039540-A2 | D-AMINO ACID OXIDASE INHIBITORS FOR LEARNING AND MEMORY | SEPRACOR INC. (US) | 2003-05-15 | — | — | WO | disclosed |