Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 2/20 | 0.38 |
| ▸ | HTR2C | P28335 | 2/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8041625 | 0.92 | EGFR (0.35) | TRPV1EGFR | |
| SCHEMBL8037400 | 0.90 | TRPV1 (0.40) | TRPV1HTR1AHTR2CHTR2ASLC6A4 | |
| SCHEMBL8038161 | 0.88 | ERN1 (0.38) | TRPV1EGFR | |
| SCHEMBL8041338 | 0.86 | KMT2A (0.45) | EGFR | |
| SCHEMBL8040095 | 0.82 | ERN1 (0.37) | — | |
| SCHEMBL8041330 | 0.82 | G6PD (0.34) | EGFR | |
| SCHEMBL8028100 | 0.80 | L3MBTL1 (0.35) | TRPV1 | |
| SCHEMBL8035729 | 0.79 | PTPN1 (0.37) | — | |
| SCHEMBL8038459 | 0.78 | TRPV1 (0.39) | TRPV1EGFRMGLLTBXA2R | |
| SCHEMBL8025578 | 0.78 | TRPV1 (0.36) | TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009081892-A1 | NOVEL CATECHOL DERIVATIVE, PHARMACEUTICAL COMPOSITION CONTAINING THE SAME, AND USE OF THOSE | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2009-07-02 | — | — | WO | disclosed |