Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | G6PD | P11413 | 1/20 | 0.34 |
| ▸ | CRHBP | P24387 | 1/20 | 0.34 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.34 |
| ▸ | TTR | P02766 | 1/20 | 0.33 |
| ▸ | ERN1 | O75460 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | COMT | P21964 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8038161 | 0.88 | ERN1 (0.38) | G6PDCRHBPCRHR2ERN1MAPT | |
| SCHEMBL8041625 | 0.86 | EGFR (0.35) | G6PDCRHBPCRHR2ERN1MAPT | |
| SCHEMBL8040095 | 0.84 | ERN1 (0.37) | G6PDCRHBPCRHR2ERN1MAPT | |
| SCHEMBL8035153 | 0.82 | TRPV1 (0.41) | EGFR | |
| SCHEMBL8028329 | 0.82 | G6PD (0.37) | G6PDCRHBPCRHR2TTRMAPT | |
| SCHEMBL8035729 | 0.81 | PTPN1 (0.37) | G6PDCRHBPCRHR2MAPTKMT2A | |
| SCHEMBL8041338 | 0.80 | KMT2A (0.45) | MAPTKMT2AEGFRPOLBKDM4E | |
| SCHEMBL8041385 | 0.78 | — | — | |
| SCHEMBL8028100 | 0.77 | L3MBTL1 (0.35) | G6PDCRHBPCRHR2ERN1MAPT | |
| SCHEMBL8028096 | 0.76 | TDP1 (0.35) | G6PDCRHBPCRHR2TTRERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009081892-A1 | NOVEL CATECHOL DERIVATIVE, PHARMACEUTICAL COMPOSITION CONTAINING THE SAME, AND USE OF THOSE | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2009-07-02 | — | — | WO | disclosed |