Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.33 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8037420 | 0.90 | KMT2A (0.39) | KMT2AALDH1A1MAPTMEN1RAB9A | |
| SCHEMBL8035153 | 0.86 | TRPV1 (0.41) | EGFR | |
| SCHEMBL8041625 | 0.86 | EGFR (0.35) | KMT2AALDH1A1MAPTMEN1KDM4E | |
| SCHEMBL8038161 | 0.83 | ERN1 (0.38) | KMT2AALDH1A1MAPTMEN1KDM4E | |
| SCHEMBL8040095 | 0.80 | ERN1 (0.37) | KMT2AALDH1A1MAPTMEN1KDM4E | |
| SCHEMBL8041330 | 0.80 | G6PD (0.34) | KMT2AALDH1A1MAPTMEN1KDM4E | |
| SCHEMBL8037400 | 0.78 | TRPV1 (0.40) | KMT2AMEN1 | |
| SCHEMBL8025491 | 0.78 | KDM4E (0.42) | KMT2AALDH1A1MAPTMEN1RAB9A | |
| SCHEMBL8035729 | 0.77 | PTPN1 (0.37) | KMT2AALDH1A1MAPTMEN1PKM | |
| SCHEMBL8028096 | 0.76 | TDP1 (0.35) | KMT2AALDH1A1MAPTMEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009081892-A1 | NOVEL CATECHOL DERIVATIVE, PHARMACEUTICAL COMPOSITION CONTAINING THE SAME, AND USE OF THOSE | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2009-07-02 | — | — | WO | disclosed |