Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TRPM8 | Q7Z2W7 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lysine SCHEMBL8025561 | 0.89 | GSR (0.40) | KDM4EALDH1A1HSD17B10TDP1HPGD | |
| Cyclohexylamine SCHEMBL8025610 | 0.89 | KDM4E (0.46) | KDM4EALDH1A1HSD17B10TDP1HPGD | |
| Piperonal SCHEMBL8025660 | 0.82 | ALDH1A1 (0.64) | KDM4EALDH1A1HSD17B10TDP1HPGD | |
| Piperonal SCHEMBL7800908 | 0.81 | HSD17B10 (0.56) | KDM4EALDH1A1HSD17B10TDP1HPGD | |
| 4-Hydroxybenzaldehyde SCHEMBL8037276 | 0.81 | ALDH5A1 (0.41) | ALDH1A1NPC1RAB9A | |
| 4-Hydroxybenzaldehyde SCHEMBL8037281 | 0.81 | ALDH5A1 (0.41) | ALDH1A1NPC1RAB9A | |
| Benzaldehyde SCHEMBL8035694 | 0.81 | KIF11 (0.42) | ALDH1A1TRPM8PTGS1 | |
| Cyclohexylamine SCHEMBL8037514 | 0.80 | GRIK1 (0.42) | ALDH1A1NPC1RAB9A | |
| Cyclohexylamine SCHEMBL8037416 | 0.80 | ALDH1A1 (0.47) | ALDH1A1RAB9A | |
| Cyclohexylamine SCHEMBL8037697 | 0.80 | GRIK1 (0.41) | ALDH1A1LMNANPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6127381-A | A MELANOCORTIN RECEPTOR LIGAND FOR REGULATING FOOD INTAKE AND BODY WEIGHT, REGULATING CYTOKINE ACTIVITY, ANTI-INFLAMMATORY ACTIVITY | LION BIOSCIENCE AG (DE) | 2000-10-03 | — | — | US | disclosed |