Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 2/20 | 0.41 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.41 |
| ▸ | DPEP1 | P16444 | 1/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 3/20 | 0.35 |
| ▸ | AGER | Q15109 | 2/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cyclohexylamine SCHEMBL8037696 | 1.00 | GRIK1 (0.41) | GRIK1GRIK2DPEP1CACNA1BKMT2A | |
| 4-Hydroxybenzaldehyde SCHEMBL8037276 | 0.89 | ALDH5A1 (0.41) | GRIK1GRIK2KMT2AALDH1A1RAB9A | |
| 4-Hydroxybenzaldehyde SCHEMBL8037281 | 0.89 | ALDH5A1 (0.41) | GRIK1GRIK2KMT2AALDH1A1RAB9A | |
| Benzaldehyde SCHEMBL8035694 | 0.88 | KIF11 (0.42) | GRIK1GRIK2KMT2AALDH1A1KIF11 | |
| Cyclohexylamine SCHEMBL8037511 | 0.88 | GRIK1 (0.42) | GRIK1GRIK2DPEP1KMT2AALDH1A1 | |
| Cyclohexylamine SCHEMBL8037514 | 0.88 | GRIK1 (0.42) | GRIK1GRIK2DPEP1KMT2AALDH1A1 | |
| Cyclohexylamine SCHEMBL8037416 | 0.88 | ALDH1A1 (0.47) | GRIK1GRIK2KMT2AALDH1A1RAB9A | |
| Cyclohexylamine SCHEMBL8037421 | 0.88 | ALDH1A1 (0.47) | GRIK1GRIK2KMT2AALDH1A1RAB9A | |
| Lysine SCHEMBL8037528 | 0.87 | GSR (0.44) | GRIK1GRIK2DPEP1CACNA1BKMT2A | |
| Lysine SCHEMBL8037527 | 0.87 | GSR (0.44) | GRIK1GRIK2DPEP1CACNA1BKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6127381-A | A MELANOCORTIN RECEPTOR LIGAND FOR REGULATING FOOD INTAKE AND BODY WEIGHT, REGULATING CYTOKINE ACTIVITY, ANTI-INFLAMMATORY ACTIVITY | LION BIOSCIENCE AG (DE) | 2000-10-03 | — | — | US | disclosed |