Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 4/20 | 0.64 |
| ▸ | APLNR | P35414 | 1/20 | 0.43 |
| ▸ | NOS3 | P29474 | 2/20 | 0.43 |
| ▸ | NOS1 | P29475 | 1/20 | 0.43 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | APAF1 | O14727 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | HK1 | P19367 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15091007 | 0.78 | NOS2 (1.00) | NOS2NOS3NOS1 | |
| SCHEMBL15091006 | 0.78 | NOS2 (1.00) | NOS2NOS3NOS1 | |
| SCHEMBL9797794 | 0.77 | NOS2 (0.40) | NOS2NOS3NOS1GRM4APP | |
| SCHEMBL9797790 | 0.77 | NOS2 (0.40) | NOS2NOS3NOS1GRM4APP | |
| SCHEMBL3088815 | 0.74 | NOS2 (0.44) | NOS2NOS3NOS1LMNAMEN1 | |
| SCHEMBL8034894 | 0.74 | NOS2 (0.44) | NOS2NOS3NOS1LMNAMEN1 | |
| SCHEMBL29600243 | 0.74 | NOS2 (0.44) | NOS2NOS3NOS1LMNAMAPT | |
| SCHEMBL1646533 | 0.74 | NOS2 (0.44) | NOS2NOS3NOS1LMNAMAPT | |
| SCHEMBL13926087 | 0.74 | NOS2 (0.46) | NOS2APLNRGRM4LMNA | |
| SCHEMBL9472907 | 0.71 | NOS3 (0.63) | NOS2NOS3NOS1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009106749-A2 | DERIVATIVES OF N-HETEROCYCLIC-IMIDAZO[1,2-A]PYRIDINE-2-CARBOXAMIDES, PREPARATION THEREOF AND THERAPEUTIC APPLICATION THEREOF | SANOFI-AVENTIS (FR) | 2009-09-03 | — | — | WO | disclosed |