SCHEMBL19968463

SCHEMBL19968463

IP(c1cc(-c2ccccc2)cc(-c2ccccc2)c1)c1cc(-c2ccccc2)cc(-c2ccccc2)c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.45
CRHBP P24387 2/20 0.38
CRHR2 Q13324 2/20 0.38
EGFR P00533 1/20 0.36
MAOA P21397 1/20 0.36
KMO O15229 1/20 0.35
CYP3A4 P08684 2/20 0.35
TDP1 Q9NUW8 2/20 0.35
MAPK1 P28482 2/20 0.35
CYP1A2 P05177 1/20 0.35
TAAR1 Q96RJ0 1/20 0.35
HSD17B10 Q99714 1/20 0.35
NOTUM Q6P988 1/20 0.35
MMP3 P08254 1/20 0.35
BCL2L1 Q07817 1/20 0.35
ALOX5 P09917 1/20 0.34
BACE1 P56817 1/20 0.33
DHODH Q02127 1/20 0.33
KDM4E B2RXH2 2/20 0.32
HTT P42858 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4332773 0.78 ALDH1A1 (0.75) ALDH1A1CRHBPCRHR2EGFRMAOA
SCHEMBL481505 0.78 ALDH1A1 (0.75) ALDH1A1CRHBPCRHR2EGFRMAOA
SCHEMBL8452262 0.78 ALDH1A1 (0.75) ALDH1A1CRHBPCRHR2EGFRMAOA
SCHEMBL8035535 0.75 ALDH1A1 (0.45) ALDH1A1CRHBPCRHR2EGFRMAOA
SCHEMBL5321294 0.74 ALDH1A1 (0.69) ALDH1A1CRHBPCRHR2EGFRMAOA
SCHEMBL5130299 0.74 ALDH1A1 (0.69) ALDH1A1CRHBPCRHR2EGFRMAOA
SCHEMBL29554408 0.74 ALDH1A1 (0.69) ALDH1A1CRHBPCRHR2EGFRMAOA
SCHEMBL4138168 0.73 ALDH1A1 (0.56) ALDH1A1CRHBPCRHR2EGFRMAOA
SCHEMBL14481975 0.72 ALDH1A1 (0.64) ALDH1A1CRHBPCRHR2MAOAKMO
SCHEMBL2939094 0.72 TDP1 (0.53) ALDH1A1CYP3A4TDP1MAPK1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113896607-B Olefin oligomerization process using a catalyst comprising a chromium complex having a phosphacycle-containing ligand 陶氏环球技术有限责任公司 2024-04-16 CN disclosed
US-20220176363-A1 PROCESS FOR OLIGOMERIZATION DOW GLOBAL TECHNOLOGIES LLC (US) 2022-06-09 US disclosed
CN-107548385-B Olefin oligomerization process using catalyst comprising chromium complex with phosphacycle-containing ligand 陶氏环球技术有限责任公司 2022-01-21 CN disclosed
CN-113896607-A Olefin oligomerization process using catalyst comprising chromium complex with phosphacycle-containing ligand 陶氏环球技术有限责任公司 2022-01-07 CN disclosed
CN-107592863-B Chromium complexes with ligands containing phosphacycles and olefin oligomerization catalysts therefrom 陶氏环球技术有限责任公司 2021-09-10 CN disclosed
CN-107567355-B Phosphacycle-containing ligands for chromium complexes and olefin oligomerization catalysts therefrom 陶氏环球技术有限责任公司 2021-07-23 CN disclosed
US-20210129125-A1 PROCESS FOR OLIGOMERIZATION DOW GLOBAL TECHNOLOGIES LLC (US) 2021-05-06 US disclosed
US-10981156-B2 Chromium complex and catalyst therefrom DOW GLOBAL TECHNOLOGIES LLC (US) 2021-04-20 US disclosed
US-10919031-B2 Process for oligomerization DOW GLOBAL TECHNOLOGIES LLC (US) 2021-02-16 US disclosed
US-20200338542-A1 PROCESS FOR OLIGOMERIZATION DOW GLOBAL TECHNOLOGIES LLC (US) 2020-10-29 US disclosed
US-10702861-B2 Process for oligomerization DOW GLOBAL TECHNOLOGIES LLC (US) 2020-07-07 US disclosed
US-20200030783-A1 PROCESS FOR OLIGOMERIZATION DOW GLOBAL TECHNOLOGIES LLC (US) 2020-01-30 US disclosed
US-10376869-B2 Process for oligomerization DOW GLOBAL TECHNOLOGIES LLC (US) 2019-08-13 US disclosed
US-10357764-B2 Phosphacycle compound and process for production thereof DOW GLOBAL TECHNOLOGIES LLC (US) 2019-07-23 US disclosed
US-20190210013-A1 CHROMIUM COMPLEX AND CATALYST THEREFROM DOW GLOBAL TECHNOLOGIES LLC (US) 2019-07-11 US disclosed
US-10207262-B2 Chromium complex and catalyst therefrom DOW GLOBAL TECHNOLOGIES LLC (US) 2019-02-19 US disclosed
US-20180154344-A1 PROCESS FOR OLIGOMERIZATION DOW GLOBAL TECHNOLOGIES LLC (US) 2018-06-07 US disclosed
US-20180071725-A1 CHROMIUM COMPLEX AND CATALYST THEREFROM DOW GLOBAL TECHNOLOGIES LLC (US) 2018-03-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (13 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210129125-A1 PROCESS FOR OLIGOMERIZATION OXER1, NOD1, LIG1 ALDH1A1 4182/4885CRHBP 2180/4885CRHR2 3230/4885
US-20200338542-A1 PROCESS FOR OLIGOMERIZATION OXER1, NOD1, LIG1 ALDH1A1 4182/4885CRHBP 2180/4885CRHR2 3230/4885
US-20180071725-A1 CHROMIUM COMPLEX AND CATALYST THEREFROM OXER1, LIG1, PICALM ALDH1A1 4013/4885CRHBP 2678/4885CRHR2 2133/4885
US-10919031-B2 Process for oligomerization OXER1, NOD1, LIG1 ALDH1A1 4182/4885CRHBP 2180/4885CRHR2 3230/4885
US-10376869-B2 Process for oligomerization OXER1, NOD1, LIG1 ALDH1A1 4182/4885CRHBP 2180/4885CRHR2 3230/4885
US-10981156-B2 Chromium complex and catalyst therefrom OXER1, LIG1, PICALM ALDH1A1 4013/4885CRHBP 2678/4885CRHR2 2133/4885
US-10357764-B2 Phosphacycle compound and process for production thereof OXER1, PPIP5K2, IP6K1 ALDH1A1 4091/4885CRHBP 2306/4885CRHR2 2690/4885
US-10207262-B2 Chromium complex and catalyst therefrom OXER1, LIG1, PICALM ALDH1A1 4013/4885CRHBP 2678/4885CRHR2 2133/4885
US-20200030783-A1 PROCESS FOR OLIGOMERIZATION OXER1, NOD1, LIG1 ALDH1A1 4182/4885CRHBP 2180/4885CRHR2 3230/4885
US-20180154344-A1 PROCESS FOR OLIGOMERIZATION OXER1, NOD1, LIG1 ALDH1A1 4182/4885CRHBP 2180/4885CRHR2 3230/4885
US-20220176363-A1 PROCESS FOR OLIGOMERIZATION OXER1, NOD1, LIG1 ALDH1A1 4182/4885CRHBP 2180/4885CRHR2 3230/4885
US-20190210013-A1 CHROMIUM COMPLEX AND CATALYST THEREFROM OXER1, LIG1, PICALM ALDH1A1 4013/4885CRHBP 2678/4885CRHR2 2133/4885
US-10702861-B2 Process for oligomerization OXER1, NOD1, LIG1 ALDH1A1 4182/4885CRHBP 2180/4885CRHR2 3230/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.