Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | MMP8 | P22894 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CASP3 | P42574 | 2/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | PTPRC | P08575 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8035614 | 0.95 | POLB (0.55) | POLBNPSR1ALDH1A1RECQLMMP8 | |
| SCHEMBL9554708 | 0.88 | POLB (0.50) | POLBNPSR1ALDH1A1RECQLMMP8 | |
| SCHEMBL9554713 | 0.88 | POLB (0.50) | POLBNPSR1ALDH1A1RECQLMMP8 | |
| SCHEMBL8035637 | 0.86 | L3MBTL1 (0.47) | NPSR1ALDH1A1KMT2AMAPK1L3MBTL1 | |
| SCHEMBL4232007 | 0.82 | NPSR1 (0.52) | POLBNPSR1ALDH1A1RECQLMMP8 | |
| SCHEMBL8037764 | 0.81 | ALDH1A1 (0.60) | POLBNPSR1ALDH1A1RECQLMMP8 | |
| SCHEMBL7435532 | 0.81 | ALDH1A1 (0.59) | POLBNPSR1ALDH1A1RECQLMMP8 | |
| SCHEMBL17460412 | 0.79 | ALDH1A1 (0.56) | POLBNPSR1ALDH1A1RECQLMMP8 | |
| SCHEMBL11285420 | 0.78 | MAPT (0.46) | POLBNPSR1ALDH1A1RECQLMMP8 | |
| SCHEMBL4419400 | 0.78 | ALDH1A1 (0.62) | POLBNPSR1ALDH1A1RECQLMMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6143787-A | HETEROCYCLIC OR AROMATIC OXOACIDS | MERCK PATENT GESELLSCHAFT MIT (DE) | 2000-11-07 | — | — | US | disclosed |