Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cyclohexylamine SCHEMBL8035776 | 1.00 | TDP1 (0.38) | TDP1L3MBTL1CTDSP1ALDH1A1TSHR | |
| Lysine SCHEMBL8039058 | 0.88 | GSR (0.42) | TDP1L3MBTL1CTDSP1ALDH1A1TSHR | |
| Lysine SCHEMBL8039060 | 0.88 | GSR (0.42) | TDP1L3MBTL1CTDSP1ALDH1A1TSHR | |
| Cyclohexylamine SCHEMBL7798067 | 0.87 | L3MBTL1 (0.41) | TDP1L3MBTL1CTDSP1ALDH1A1TSHR | |
| Aes-103 SCHEMBL8025663 | 0.85 | ALDH1A1 (0.50) | TDP1ALDH1A1TSHRKIF11GRIK1 | |
| Aes-103 SCHEMBL8025669 | 0.85 | ALDH1A1 (0.50) | TDP1ALDH1A1TSHRKIF11GRIK1 | |
| Cyclohexylamine SCHEMBL7802602 | 0.83 | TDP1 (0.40) | TDP1L3MBTL1CTDSP1ALDH1A1TSHR | |
| Cyclohexylamine SCHEMBL8025516 | 0.82 | CASP6 (0.44) | TDP1L3MBTL1ALDH1A1SMN1; SMN2LMNA | |
| Cyclohexylamine SCHEMBL8025520 | 0.82 | CASP6 (0.44) | TDP1L3MBTL1ALDH1A1SMN1; SMN2LMNA | |
| Cyclohexylamine SCHEMBL8039236 | 0.80 | ALDH1A1 (0.43) | TDP1L3MBTL1ALDH1A1TSHRKIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6127381-A | A MELANOCORTIN RECEPTOR LIGAND FOR REGULATING FOOD INTAKE AND BODY WEIGHT, REGULATING CYTOKINE ACTIVITY, ANTI-INFLAMMATORY ACTIVITY | LION BIOSCIENCE AG (DE) | 2000-10-03 | — | — | US | disclosed |