Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 2/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.34 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.34 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lysine SCHEMBL8035898 | 0.88 | GSR (0.43) | ALDH1A1POLBTDP1L3MBTL1KIF11 | |
| Cyclohexylamine SCHEMBL7800295 | 0.86 | ALDH1A1 (0.49) | ALDH1A1POLBTDP1L3MBTL1HCAR2 | |
| Cyclohexylamine SCHEMBL7801667 | 0.83 | ALDH1A1 (0.62) | ALDH1A1POLBTDP1L3MBTL1HCAR2 | |
| Benzaldehyde SCHEMBL8035694 | 0.81 | KIF11 (0.42) | ALDH1A1KIF11MEN1KMT2A | |
| Cyclohexylamine SCHEMBL8035776 | 0.80 | TDP1 (0.38) | ALDH1A1POLBTDP1L3MBTL1KIF11 | |
| Cyclohexylamine SCHEMBL8035772 | 0.80 | TDP1 (0.38) | ALDH1A1POLBTDP1L3MBTL1KIF11 | |
| Aes-103 SCHEMBL8025669 | 0.79 | ALDH1A1 (0.50) | ALDH1A1TDP1KIF11TSHR | |
| Aes-103 SCHEMBL8025663 | 0.79 | ALDH1A1 (0.50) | ALDH1A1TDP1KIF11TSHR | |
| Cyclohexylamine SCHEMBL8037665 | 0.79 | HCAR2 (0.35) | ALDH1A1KIF11HCAR2SLC1A3SLC1A2 | |
| Cyclohexylamine SCHEMBL8037416 | 0.78 | ALDH1A1 (0.47) | ALDH1A1KIF11KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6127381-A | A MELANOCORTIN RECEPTOR LIGAND FOR REGULATING FOOD INTAKE AND BODY WEIGHT, REGULATING CYTOKINE ACTIVITY, ANTI-INFLAMMATORY ACTIVITY | LION BIOSCIENCE AG (DE) | 2000-10-03 | — | — | US | disclosed |