Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 2/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13658185 | 0.80 | CYP2D6 (0.47) | SIGMAR1SLC6A2TAAR1MAOASLC6A4 | |
| Bromide SCHEMBL6229520 | 0.77 | NPC1 (0.63) | TAAR1MAOACYP2A6NPC1POLB | |
| SCHEMBL5306247 | 0.75 | NPC1 (0.44) | NPC1POLBRAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL6231742 | 0.74 | NPC1 (0.60) | TAAR1MAOACYP2A6NPC1POLB | |
| Bromide SCHEMBL8025979 | 0.74 | TP53 (0.45) | AOC3SLC6A2TAAR1MAOASLC6A4 | |
| SCHEMBL5810465 | 0.74 | SMN1; SMN2 (0.50) | SLC6A2SLC6A4SLC6A3NPC1POLB | |
| SCHEMBL5327172 | 0.74 | KDM4E (0.38) | SIGMAR1SLC6A2TAAR1MAOASLC6A4 | |
| Bromide SCHEMBL11799324 | 0.73 | ALDH1A1 (0.37) | TAAR1MAOACYP2A6NPC1POLB | |
| Hydrochloric Acid SCHEMBL8857341 | 0.73 | RAB9A (0.58) | TAAR1MAOANPC1POLBRAB9A | |
| SCHEMBL5303543 | 0.72 | SMN1; SMN2 (0.53) | SLC6A2SLC6A4SLC6A3NPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0820607-B1 | PHOTOGRAPHIC SYSTEM | POLAROID CORP (US) | 2000-03-22 | — | — | EP | disclosed |
| EP-0820607-A1 | PHOTOGRAPHIC SYSTEM | POLAROID CORPORATION (US) | 1998-01-28 | — | — | EP | disclosed |
| US-5705312-A | PHOTOGRAPHIC FILM DEVELOPMENT OF SILVER HALIDE EMULSIONS TO FORM IMAGES ON SHEETS WITH RUPTURABLE CONTAINERS | POLAROID CORPORATION (US) | 1998-01-06 | — | — | US | disclosed |
| WO-1997029405-A1 | PHOTOGRAPHIC SYSTEM | POLAROID CORPORATION (US) | 1997-08-14 | — | — | WO | disclosed |
| US-4123330-A | Color diffusion transfer process using benzyl alcohol and derivatives thereof | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1978-10-31 | — | — | US | disclosed |